Formal total synthesis of ovalcin by carbohydrate approach

被引：13

作者：

Yadav, Jhillu Singh ^{[1
]}

Pamu, Sreedhar ^{[1
]}

Bhunia, Dinesh Chandra ^{[1
]}

Pabbaraja, Srihari ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNLETT | 2007年 / 06期

关键词：

angiogenesis; metathesis; ring opening; epoxidation; ANGIOGENESIS INHIBITOR TNP-470; DIMETHYL-SULFOXIDE; ALLYLIC ALCOHOLS; OXALYL CHLORIDE; L-QUEBRACHITOL; FUMAGILLIN; CANCER; (-)-OVALICIN; OXIDATION; ANALOGS;

D O I：

10.1055/s-2007-970767

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A formal total synthesis of ovalcin is described herein starting from readily available sugar ribose with selective zinc-mediated ring-opening reaction and Grubbs olefin metathesis as the key steps.

引用

页码：992 / 994

页数：3

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