Should A Tidal Volume of 6 mL/kg Be Used in All Patients?

被引：23

作者：

Davies, John D. ^{[1
]}

Senussi, Mourad H. ^{[2
]}

Mireles-Cabodevila, Eduardo ^{[2
]}

机构：

[1] Duke Univ, Resp Care Serv, Box 3911, Durham, NC 27710 USA

[2] Cleveland Clin, Resp Inst, 9500 Euclid Ave,A90, Cleveland, OH 44195 USA

来源：

RESPIRATORY CARE | 2016年 / 61卷 / 06期

关键词：

tidal volume; predicted body weight; mechanical ventilation; lung-protective ventilation; time constant; ARDS; stress; strain; hypercapnia; RESPIRATORY-DISTRESS-SYNDROME; ACUTE LUNG INJURY; RANDOMIZED CONTROLLED-TRIAL; ACUTE SEVERE ASTHMA; PROTECTIVE MECHANICAL VENTILATION; END-EXPIRATORY PRESSURE; HIGH AIRWAY PRESSURE; HYPERCAPNIC ACIDOSIS; ABDOMINAL-SURGERY; PULMONARY COMPLICATIONS;

D O I：

10.4187/respcare.04651

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

It has been shown that mechanical ventilation by itself can cause lung injury and affect outcomes. Ventilator-induced lung injury is associated with high tidal volumes in lungs afflicted with ARDS. However, the question is: Do high tidal volumes have this same effect in normal lungs or lungs that have respiratory compromise stemming from something other than ARDS? Many clinicians believe that a tidal volume strategy of 6 mL/kg predicted body weight should be standard practice in all patients receiving mechanical ventilation. There is a growing body of evidence related to this issue, and this is the debate that will be tackled in this paper from both pro and con perspectives. (C) 2016 Daedalus Enterprises

引用

页码：774 / 787

页数：14

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