Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018

被引:20
作者
Pohlmann, Anne [1 ]
Hoffmann, Donata [1 ]
Grund, Christian [1 ]
Koethe, Susanne [1 ]
Huessy, Daniela [2 ]
Meier, Simone M. [3 ]
King, Jacqueline [1 ]
Schinkoethe, Jan [1 ]
Ulrich, Reiner [1 ]
Harder, Timm [1 ]
Beer, Martin [1 ]
机构
[1] Friedrich Loeffler Inst, Influenza Virus Sequence Anal, Inst Diagnost Virol, Greifswald, Germany
[2] Inst Virol & Immunol, Mittelhausern, Switzerland
[3] Vetsuisse Fac Zurich, Zurich, Switzerland
关键词
WILD BIRDS;
D O I
10.3201/eid2510.181931
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We genetically characterized highly pathogenic avian influenza virus A(H5N6) Glade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment.
引用
收藏
页码:1973 / 1976
页数:4
相关论文
共 13 条
[11]   Swarm incursions of reassortants of highly pathogenic avian influenza virus strains H5N8 and H5N5, clade 2.3.4.4b, Germany, winter 2016/17 [J].
Pohlmann, Anne ;
Starick, Elke ;
Grund, Christian ;
Hoeper, Dirk ;
Strebelow, Guenter ;
Globig, Anja ;
Staubach, Christoph ;
Conraths, Franz J. ;
Mettenleiter, Thomas C. ;
Harder, Timm ;
Beer, Martin .
SCIENTIFIC REPORTS, 2018, 8
[12]   Outbreaks among Wild Birds and Domestic Poultry Caused by Reassorted Influenza A(H5N8) Clade 2.3.4.4 Viruses, Germany, 2016 [J].
Pohlmann, Anne ;
Starick, Elke ;
Harder, Timm ;
Grund, Christian ;
Hoeper, Dirk ;
Globig, Anja ;
Staubach, Christoph ;
Dietze, Klaas ;
Strebelow, Guenter ;
Ulrich, Reiner G. ;
Schinkoethe, Jan ;
Teifke, Jens P. ;
Conraths, Franz J. ;
Mettenleiter, Thomas C. ;
Beer, Martin .
EMERGING INFECTIOUS DISEASES, 2017, 23 (04) :633-636
[13]  
World Health Organization, 2018, ANT GEN CHAR ZOON IN