Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018

被引：20

作者：

Pohlmann, Anne ^{[1
]}

Hoffmann, Donata ^{[1
]}

Grund, Christian ^{[1
]}

Koethe, Susanne ^{[1
]}

Huessy, Daniela ^{[2
]}

Meier, Simone M. ^{[3
]}

King, Jacqueline ^{[1
]}

Schinkoethe, Jan ^{[1
]}

Ulrich, Reiner ^{[1
]}

Harder, Timm ^{[1
]}

Beer, Martin ^{[1
]}

机构：

[1] Friedrich Loeffler Inst, Influenza Virus Sequence Anal, Inst Diagnost Virol, Greifswald, Germany

[2] Inst Virol & Immunol, Mittelhausern, Switzerland

[3] Vetsuisse Fac Zurich, Zurich, Switzerland

来源：

EMERGING INFECTIOUS DISEASES | 2019年 / 25卷 / 10期

关键词：

WILD BIRDS;

D O I：

10.3201/eid2510.181931

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We genetically characterized highly pathogenic avian influenza virus A(H5N6) Glade 2.3.4.4b isolates found in Germany in 2017-2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however, continued characterization of related isolates is warranted because of their high potential for reassortment.

引用

页码：1973 / 1976

页数：4

共 13 条

[1] Novel Highly Pathogenic Avian Influenza A(H5N6) Virus in the Netherlands, December 2017 [J].

Beerens, Nancy ;

Koch, Guus ;

Heutink, Rene ;

Harders, Frank ;

Vries, D. P. Edwin ;

Ho, Cynthia ;

Bossers, Alex ;

Elbers, Armin .

EMERGING INFECTIOUS DISEASES, 2018, 24 (04) :770-773

[2] Multiple Reassorted Viruses as Cause of Highly Pathogenic Avian Influenza A(H5N8) Virus Epidemic, the Netherlands, 2016 [J].

Beerens, Nancy ;

Heutink, Rene ;

Bergervoet, Saskia A. ;

Harders, Frank ;

Bossers, Alex ;

Koch, Guus .

EMERGING INFECTIOUS DISEASES, 2017, 23 (12) :1966-1973

[3] Pathogenicity testing of influenza candidate vaccine viruses in the ferret model [J].

Belser, Jessica A. ;

Johnson, Adam ;

Pulit-Penaloza, Joanna A. ;

Pappas, Claudia ;

Pearce, Melissa B. ;

Tzeng, Wen -Pin ;

Hossain, M. Jaber ;

Ridenour, Callie ;

Wang, Li ;

Chen, Li-Mei ;

Wentworth, David E. ;

Katz, Jacqueline M. ;

Maines, Taronna R. ;

Tumpey, Terrence M. .

VIROLOGY, 2017, 511 :135-141

[4] Genetic Diversity of Highly Pathogenic Avian Influenza A(H5N8/H5N5) Viruses in Italy, 2016-17 [J].

Fusaro, Alice ;

Monne, Isabella ;

Mulatti, Paolo ;

Zecchin, Bianca ;

Bonfanti, Lebana ;

Ormelli, Silvia ;

Milani, Adelaide ;

Cecchettin, Krizia ;

Lemey, Philippe ;

Moreno, Ana ;

Massi, Paola ;

Dorotea, Tiziano ;

Marangon, Stefano ;

Terregino, Calogero .

EMERGING INFECTIOUS DISEASES, 2017, 23 (09) :1543-1547

[5]

Globig A, 2013, FRONT VET SCI, DOI [10.3201/EID2404.172124, DOI 10.3201/EID2404.172124]

[6] A novel European H5N8 influenza A virus has increased virulence in ducks but low zoonotic potential [J].

Grund, Christian ;

Hoffmann, Donata ;

Ulrich, Reiner ;

Naguib, Mahmoud ;

Schinkoethe, Jan ;

Hoffmann, Bernd ;

Harder, Timm ;

Saenger, Sandra ;

Zscheppang, Katja ;

Toennies, Mario ;

Hippenstiel, Stefan ;

Hocke, Andreas ;

Wolff, Thorsten ;

Beer, Martin .

EMERGING MICROBES & INFECTIONS, 2018, 7

[7] Deaths among Wild Birds during Highly Pathogenic Avian Influenza A(H5N8) Virus Outbreak, the Netherlands [J].

Kleyheeg, Erik ;

Slaterus, Roy ;

Bodewes, Rogier ;

Rijks, Jolianne M. ;

Spierenburg, Marcel A. H. ;

Beerens, Nancy ;

Kelder, Leon ;

Poen, Marjolein J. ;

Stegeman, Jan A. ;

Fouchier, Ron A. M. ;

Kuiken, Thijs ;

van der Jeugd, Henk P. .

EMERGING INFECTIOUS DISEASES, 2017, 23 (12) :2050-2054

[8] Comparison of the pathogenic potential of highly pathogenic avian influenza (HPAI) H5N6, and H5N8 viruses isolated in South Korea during the 2016-2017 winter season [J].

Kwon, Hyeok-il ;

Kim, Eun-Ha ;

Kim, Young-il ;

Park, Su-Jin ;

Si, Young-Jae ;

Lee, In-Won ;

Hiep Dinh Nguyen ;

Yu, Kwang Min ;

Yu, Min-Ah ;

Jung, Ju Hwan ;

Choi, Won-Suk ;

Kwon, Jin Jung ;

Ahn, Su Jeong ;

Baek, Yun Hee ;

Lai, Dam Van ;

Lee, Ok-Jun ;

Kim, Si-Wook ;

Song, Min-Suk ;

Yoon, Sun-Woo ;

Kim, Chul-Joong ;

Webby, Richard J. ;

Mo, In-Pil ;

Choi, Young Ki .

EMERGING MICROBES & INFECTIONS, 2018, 7

[9] Limited pathogenicity and transmissibility of Korean highly pathogenic avian influenza H5N6 clade 2.3.4.4 in ferrets [J].

Noh, J. -Y. ;

Lee, D. -H. ;

Yuk, S. -S. ;

Kwon, J. -H. ;

Tseren-Ochir, E. -O. ;

Hong, W. -T. ;

Jeong, J. -H. ;

Jeong, S. ;

Song, C. -S. .

TRANSBOUNDARY AND EMERGING DISEASES, 2018, 65 (04) :923-926

[10] Co-circulation of genetically distinct highly pathogenic avian influenza A clade 2.3.4.4 (H5N6) viruses in wild waterfowl and poultry in Europe and East Asia, 2017-18 [J].

Poen, Marjolein J. ;

Venkatesh, Divya ;

Bestebroer, Theo M. ;

Vuong, Oanh ;

Scheuer, Rachel D. ;

Munnink, Bas B. Oude ;

de Meulder, Dennis ;

Richard, Mathilde ;

Kuiken, Thijs ;

Koopmans, Marion P. G. ;

Kelder, Leon ;

Kim, Yong-Joo ;

Lee, Youn-Jeong ;

Steensels, Mieke ;

Lambrecht, Benedicte ;

Dan, Adam ;

Pohlmann, Anne ;

Beer, Martin ;

Savic, Vladimir ;

Brown, Ian H. ;

Fouchier, Ron A. M. ;

Lewis, Nicola S. .

VIRUS EVOLUTION, 2019, 5 (01)

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