PET and PET-CT CT in radiation treatment planning for lung cancer

被引：3

作者：

Aristei, Cynthia ^{[1
]}

Falcinelli, Lorenzo ^{[1
]}

Palumbo, Barbara ^{[2
]}

Tarducci, Roberto ^{[3
]}

机构：

[1] Univ Perugia, Osped Santa Maria della Misericordia, Dept Surg Radiol & Odontostomatol Sci, Radiat Oncol Sect, I-06156 Perugia, Italy

[2] Univ Perugia, Osped Santa Maria della Misericordia, Dept Surg Radiol & Odontostomatol Sci, Nucl Med Sect, I-06156 Perugia, Italy

[3] Osped S Maria Misericordia, Perugia Gen Hosp, Med Phys Unit, I-06156 Perugia, Italy

来源：

EXPERT REVIEW OF ANTICANCER THERAPY | 2010年 / 10卷 / 04期

关键词：

3D conformal radiotherapy; contouring; image co-registration; lung cancer; PET/PET-CT; target definition; POSITRON-EMISSION-TOMOGRAPHY; GROSS TUMOR VOLUME; UNSUSPECTED DISTANT METASTASES; STANDARDIZED UPTAKE VALUE; FDG-PET; TARGET VOLUME; CONFORMAL RADIOTHERAPY; DOSE-ESCALATION; IMAGE FUSION; LYMPH-NODES;

D O I：

10.1586/ERA.09.195

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This review analyzes PET images in radiotherapy treatment planning for lung cancer patients and discusses the most controversial current issues. Computed tomography images are commonly used to assess location and extension of target volumes and organs at risk in radiotherapy treatment planning. Although PET is more sensitive and specific, contouring on PET images is difficult because tumor margins are indistinct, due to heterogeneous (18)fluorodeoxyglucose uptake distribution and limited spatial resolution. The best target delineation criteria have not yet been established. In non-small-cell lung cancer, PET appears to improve sparing of organs at risk and reduce the risk of toxicity; prescribed doses can be increased. Data are scarce on small-cell lung cancer.

引用

页码：571 / 584

页数：14

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