In vitro antitumour activity of some organogermanium radioprotectors

被引：11
作者：
Célariès, B
Gielen, M
de Vos, D
Rima, G
机构：
[1] Univ Toulouse 3, UMR 5069 CNRS, Lab Heterochim Fondamentale & Appl, F-31062 Toulouse 4, France
[2] Free Univ Brussels VUB, Fac Sci Appl, POSC Dept, B-1050 Brussels, Belgium
[3] PCH Nederland, Pharmachem BV, Dept Med, NL-2003 RN Haarlem, Netherlands
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 2003年 / 17卷 / 03期
关键词：
antitumour activity; selenagermaadamantane; organogermanium radioprotector;
D O I：
10.1002/aoc.403
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Four germanium derivatives of 2,2'-oxydiethanethiol and 2,2'-thiodiethanethiol have been synthesized and characterized by H-1 and C-13 NMR, mass spectroscopy and elemental analysis. The antitumour activity of one of them is comparable to those of cis-platin and etoposide. Copyright (C) 2003 John Wiley Sons, Ltd.
引用
收藏
页码：191 / 193
页数：3
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