Fabrication of fluorescent biosensing platform based on graphene oxide-DNA and their application in biomolecule detection

被引:24
作者
Wang, Si-Ying [1 ]
Wang, Chen-Feng [1 ]
Lv, Yun-Kai [1 ,2 ]
Shen, Shi-Gang [1 ,2 ]
机构
[1] Hebei Univ, Key Lab Analyt Sci & Technol Hebei Prov, Coll Chem & Environm Sci, Baoding 071002, Peoples R China
[2] Hebei Univ, Minist Educ, Key Lab Med Chem & Mol Diag, Baoding 071002, Peoples R China
基金
中国国家自然科学基金;
关键词
Graphene oxide; DNA; Fluorescent biosensors; Biomolecule; RESONANCE ENERGY-TRANSFER; AGGREGATION-INDUCED EMISSION; HYBRIDIZATION CHAIN-REACTION; ROLLING CIRCLE AMPLIFICATION; LABEL-FREE; SIGNAL AMPLIFICATION; ENZYME-FREE; TERMINAL PROTECTION; SENSITIVE DETECTION; GOLD NANOPARTICLES;
D O I
10.1016/j.trac.2018.07.004
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
During the past few years, graphene oxide (GO) becomes increasingly significant in fluorescent biosensing due to its unique heterogeneous structure that offers it potential applications in various fields. Based on the transformation of affinities between GO and DNA, plenty of assays for bioanalysis have been developed rapidly, in which GO generally functions as a quencher. In this review, the current status and design mechanism of fluorescent biosensing platform based on graphene oxide-DNA are introduced in detail; the latest research progress of biomolecular fluorescence sensing has been summarized, classified and compared in this paper. Some unique and elegant ideas are introduced. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:53 / 61
页数:9
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