Efficient synthetic procedure to new 2-imino-1,3-thiazolines and thiazolidin-4-ones promoted by acetonitrile electrogenerated base

被引：14

作者：

Haouas, Beya ^{[1
]}

Sbei, Najwa ^{[1
]}

Ayari, Hana ^{[1
]}

Benkhoud, M. Lamine ^{[1
]}

Batanero, Belen ^{[2
,3
]}

机构：

[1] Univ Tunis El Manar, Fac Sci, Lab Chim Analyt & Electrochim, Tunis 2092, Tunisia

[2] Univ Alcala De Henares, Dept Organ Chem, Alcala De Henares 28871, Madrid, Spain

[3] Univ Alcala De Henares, Inst Invest Quim Andres M del Rio IQAR, Alcala De Henares 28871, Madrid, Spain

来源：

NEW JOURNAL OF CHEMISTRY | 2018年 / 42卷 / 14期

关键词：

ONE-POT SYNTHESIS; DERIVATIVES; THIAZOLIDINE-2,4-DIONES; 4-THIAZOLIDINONES; CYCLIZATION; FACILE; DESIGN; AGENTS; ACIDS;

D O I：

10.1039/c8nj01992d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel and convenient strategy is described for the regioselective conversion of N,N-disubstituted thioureas and 1,2-dielectrophiles into the highly biologically valuable 2-imino-thiazoline and 2-imino thiazolidine-4-one derivatives. The synthesis proceeds through a process with good yield promoted by an electrogenerated base (EGB) obtained with high current efficiency.

引用

页码：11776 / 11781

页数：6

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