The flow inside an idealised form of the human extra-thoracic airway

被引:65
作者
Johnstone, A
Uddin, M
Pollard, A [1 ]
Heenan, A
Finlay, WH
机构
[1] Queens Univ, Dept Mech Engn, Kingston, ON K7L 3N6, Canada
[2] Ferrari Gest Sport, I-41053 Maranello, Italy
[3] Univ Alberta, Dept Mech Engn, Edmonton, AB T6G 2G8, Canada
关键词
D O I
10.1007/s00348-004-0857-4
中图分类号
TH [机械、仪表工业];
学科分类号
0802 ;
摘要
The mean and RMS axial velocity field in the central sagittal plane of an idealized representation of the human extrathoracic airway (ETA) during steady inspiration was studied experimentally using single and X-hot-wire anemometry (HWA). Complementary flow-visualization results illustrate the complex nature of this flow, which includes several regions of separated, secondary, and recirculating flow. Hot-wire experiments attest to this complexity, with several regions of high localized turbulence intensity measured distal to the oropharynx. Physiologically accurate flow rates of 10, 15, 30, 45, 60, 90 and 120 l/min are considered. These flow rates encompass a wide range of respiratory patterns, from normal breathing to the rapid inhalation typically encountered during the use of pharmaceutical aerosol inhalation devices.
引用
收藏
页码:673 / 689
页数:17
相关论文
共 34 条
[1]  
[Anonymous], 1992, DRUGS PHARM SCI
[2]   FLOW IN CURVED PIPES [J].
BERGER, SA ;
TALBOT, L ;
YAO, LS .
ANNUAL REVIEW OF FLUID MECHANICS, 1983, 15 :461-512
[3]  
BROWNE LWB, 1989, EXP FLUIDS, V7, P201
[4]  
Brucker C, 1998, PHYS FLUIDS, V10, P877, DOI 10.1063/1.869611
[5]  
Brunn H. H., 1995, HOT WIRE ANEMOMETRY
[6]   DISPERSION OF INDICATOR FLOWING THROUGH SIMPLIFIED MODELS OF CIRCULATION AND ITS RELEVANCE TO VELOCITY PROFILE IN BLOOD VESSELS [J].
CARO, CG .
JOURNAL OF PHYSIOLOGY-LONDON, 1966, 185 (03) :501-&
[7]   A MODEL STUDY OF FLOW DYNAMICS IN HUMAN CENTRAL AIRWAYS .1. AXIAL VELOCITY PROFILES [J].
CHANG, HK ;
ELMASRY, OA .
RESPIRATION PHYSIOLOGY, 1982, 49 (01) :75-95
[8]   CHLAMYDIA-TRACHOMATIS IN OTITIS-MEDIA IN CHILDREN [J].
CHANG, MJ ;
RODRIGUEZ, WJ ;
MOHLA, C .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1982, 1 (02) :95-97
[9]   Nasal deposition of ultrafine particles in human volunteers and its relationship to airway geometry [J].
Cheng, YS ;
Yeh, HC ;
Guilmette, RA ;
Simpson, SQ ;
Cheng, KH ;
Swift, DL .
AEROSOL SCIENCE AND TECHNOLOGY, 1996, 25 (03) :274-291
[10]   Flow structures and particle deposition patterns in double-bifurcation airway models. Part 1. Air flow fields [J].
Comer, JK ;
Kleinstreuer, C ;
Zhang, Z .
JOURNAL OF FLUID MECHANICS, 2001, 435 :25-54