Screening for Down's syndrome: the effect of test date on the detection rate

被引：12

作者：

Dunstan, FDJ

Nix, ABJ

机构：

[1] Univ Wales Coll Med, Dept Med Comp & Stat, Cardiff CF4 4XN, S Glam, Wales

[2] Univ Wales, Sch Math, Cardiff CF2 4YH, S Glam, Wales

来源：

ANNALS OF CLINICAL BIOCHEMISTRY | 1998年 / 35卷

关键词：

trisomy; 21; gestational age;

D O I：

10.1177/000456329803500106

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Screening tests for Down's syndrome are carried out at different gestational ages. Because of fetal loss, crude estimates of their detection rates cannot be directly compared. We present methods for estimating the true detection rates along with their standard errors. This enables a proper statistical comparison of the true detection rates of tests carried out, for example, in different trimesters.

引用

页码：57 / 61

页数：5

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