Anal verrucous carcinoma and penile condylomata acuminata

被引:10
作者
Lu, S
Bodemer, W
Ostwald, C
Barten, M
Zimmermann, R
Seipp, C
Gross, G
机构
[1] Univ Rostock, Dept Dermatovenereol, D-18055 Rostock, Germany
[2] Univ Rostock, Dept Pathol, D-18055 Rostock, Germany
关键词
verrucous carcinoma; Buschke-Loewenstein tumor; human papillomavirus type 6; polymerase chain reaction; southern blot hybridization; adjuvant interferon therapy;
D O I
10.1159/000018396
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
A 50-year-old man presented with recurrent tumorous lesions on the penis and the anal region. The anal lesion was histologically diagnosed as verrucous carcinoma (VC) and the penile lesions were in line with condylomata acuminata. Samples taken from tumors of both sites were human papillomavirus (HPV) DNA positive. Two of them taken from the penis and the perianal region scored HPV DNA 6 positive by using polymerase chain reaction and the Southern blot method. Treatment of both VC and condylomata acuminata consisted in surgery and adjuvant immune therapy. Neither tumor recurrence nor metastases occurred up until 6 months after therapy. Copyright (C) 2000 S. Karger AG, Basel.
引用
收藏
页码:320 / 323
页数:4
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