Omega-3 (n-3) fatty acids in health and disease:: Part I -: Cardiovascular disease and cancer

被引:111
作者
Shahidi, F [1 ]
Miraliakbari, H [1 ]
机构
[1] Mem Univ Newfoundland, Dept Biochem, St John, NF A1B 3X9, Canada
关键词
cancer development; cardiovascular health; omega-3 fatty acids;
D O I
10.1089/jmf.2004.7.387
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The omega-3 (n-3) polyunsaturated fatty acids have a wide range of beneficial effects in several human health conditions. Animal and in vitro studies have indicated that omega-3 fatty acids affect blood lipid profiles, cardiovascular health, membrane lipid composition, eicosanoid biosynthesis, cell signaling cascades, and gene expression. Findings from epidemiological studies suggest that intake of omega-3 fatty acids from natural Sources or supplements may influence the onset and progression of several disease states, including cardiovascular disease and cancer. This review highlights some recent research findings that help advance our understanding of how omega-3 fatty acids influence cardiovascular disease and cancer.
引用
收藏
页码:387 / 401
页数:15
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