Reductive coupling reaction of benzyl, allyl and alkyl halides in aqueous medium promoted by zinc

被引：21

作者：

de Sá, ACPF ^{[1
]}

Pontes, GMA ^{[1
]}

dos Anjos, JAL ^{[1
]}

Santana, SR ^{[1
]}

Bieber, LW ^{[1
]}

Malvestiti, I ^{[1
]}

机构：

[1] Univ Fed Pernambuco, Dept Quim Fundamental, BR-50670901 Recife, PE, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2003年 / 14卷 / 03期

关键词：

homocoupling reaction; organic halides; aqueous media;

D O I：

10.1590/S0103-50532003000300015

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Organic halides undergo reductive dimerization (Wurtz-type coupling) promoted by zinc at room temperature in aqueous medium. The reaction yields are strongly enhanced by copper catalysis. This coupling procedure provides an efficient and simple method for the homocoupling of benzylic and allylic bromides and primary alkyl iodides.

引用

页码：429 / 434

页数：6

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