Mitochondria and calcium homeostasis.

被引：0

作者：

Chen, LY ^{[1
]}

Zou, SB ^{[1
]}

Kang, HG ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Inst Biochem & Biophys, Wuhan 430074, Peoples R China

来源：

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 2000年 / 27卷 / 05期

关键词：

mitochondria; calcium homeostasis; calcium microdomain; Na+/Ca2+ exchanger;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

It had been a long time to study the effect of mitochondria in the regulation of cytosolic calcium signal. Recently, following the development of new method and technology, it is found that mitochondria plays an important role in calcium signaling. Mitochondria can sense the existence of surrounding calcium microdomains and uptake Ca2+. It can also release Ca2+ through 2Na(+)/Ca2+ exchanger and mitochondrial permeablize transition pore. Therefore, the time-spatio characteristic of cytosolic calcium signal can be regulated and related cellular function can be affected by mitochondria. However, due to the limitation of technique used now, confused and contradictory results are often obtained and further exploration is needed.

引用

页码：483 / 488

页数：6

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