Acute ophthalmoparesis associated with Anti-GM1, Anti-GD1a, and Anti-GD1b antibodies after enterovirus infection in a 6-year-old girl

被引:8
作者
Fusco, Carlo [1 ]
Bertani, Gianna [1 ]
Scarano, Angela [1 ]
Della Giustina, Elvio [1 ]
机构
[1] Arcisped Santa Maria Nuova, Child Neurol Univ, I-42100 Reggio Emilia, Italy
关键词
antiganglioside antibodies; ophthalmoparesis; GM1; GD1a; GD1b;
D O I
10.1177/0883073807301921
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This article presents a 6-year-old girl who developed acute unilateral third cranial nerve palsy in the absence of any other sign of central nervous system involvement. Raised titers of immunoglobulin M antibodies against GM1, GD1a, and GD1b ganglioside components were demonstrated. Ten days earlier, the girl had experienced acute gastroenteritis with positive specific immunoglobulin M antibodies against enterovirus. The results of all other laboratory tests usually performed for infectious diseases were negative, and neuroradiologic findings were also normal. Oral prednisone was
引用
收藏
页码:432 / 434
页数:3
相关论文
共 10 条
[1]   Recurrent anti-GQ1b IgG antibody syndrome showing different phenotypes in different periods [J].
Hamaguchi, T ;
Yamaguchi, K ;
Komai, K ;
Yamada, M ;
Yokoji, H ;
Satake, R ;
Yoshino, H .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2003, 74 (09) :1350-1350
[2]  
Kikuchi M, 1997, Eur J Paediatr Neurol, V1, P47, DOI 10.1016/S1090-3798(97)80011-6
[3]   Anti-GMI antibodies: the cause of otherwise unexplained ophthalmoplegias? [J].
Kowal, L ;
Gajus, MA ;
Kornberg, AJ .
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2004, 32 (04) :411-414
[4]   Post-infectious ophtalmoparesis associated with anti-GM1 but not with anti-GQ1b antibodies [J].
Lavallée, P ;
Vidailhet, M ;
Dussaule, JC ;
Derkinderen, P .
EUROPEAN JOURNAL OF NEUROLOGY, 2001, 8 (05) :475-476
[5]   Serum antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in Miller Fisher syndrome [J].
Neisser, A ;
Bernheimer, H ;
Berger, T ;
Moran, AP ;
Schwerer, B .
INFECTION AND IMMUNITY, 1997, 65 (10) :4038-4042
[6]   Anti-GQ1b IgG antibody syndrome: clinical and immunological range [J].
Odaka, M ;
Yuki, N ;
Hirata, K .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2001, 70 (01) :50-55
[7]  
Ryo M, 1994, Rinsho Shinkeigaku, V34, P702
[8]  
Weber P, 2003, NEUROPEDIATRICS, V34, P274
[9]   Peripheral neuropathies and anti-glycolipid antibodies [J].
Willison, HJ ;
Yuki, N .
BRAIN, 2002, 125 :2591-2625
[10]   Acute ophthalmoparesis (without ataxia) associated with anti-GQ1b IgG antibody - Clinical features [J].
Yuki, N ;
Odaka, M ;
Hirata, K .
OPHTHALMOLOGY, 2001, 108 (01) :196-200