Metabolic control: A new solution to an old problem

被引:30
作者
Hardie, DG [1 ]
机构
[1] Univ Dundee, Sch Life Sci, Wellcome Trust Bioctr, Dundee DD1 5EH, Scotland
基金
英国医学研究理事会; 英国惠康基金;
关键词
D O I
10.1016/S0960-9822(00)00744-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The phenomenon whereby the presence of oxygen regulates the rate of glucose metabolism was first described by Louis Pasteur. A novel mechanism has now been discovered, involving the AMP-activated protein kinase cascade, that can account for the Pasteur effect in ischaemic heart muscle.
引用
收藏
页码:R757 / R759
页数:3
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