Science in the cloud (SIC): A use case in MRI connectomics

被引:18
作者
Kiar, Gregory [1 ,2 ]
Gorgolewski, Krzysztof J. [3 ]
Kleissas, Dean [4 ]
Roncal, William Gray [4 ,5 ]
Litt, Brian [6 ,7 ]
Wandell, Brian [3 ,8 ]
Poldrack, Russel A. [3 ]
Wiener, Martin [9 ]
Vogelstein, R. Jacob
Burns, Randal [5 ]
Vogelstein, Joshua T. [1 ,2 ]
机构
[1] Johns Hopkins Univ, Dept Biomed Engn, Baltimore, MD USA
[2] Johns Hopkins Univ, Ctr Imaging Sci, Baltimore, MD USA
[3] Stanford Univ, Dept Psychol, Stanford, CA 94305 USA
[4] Johns Hopkins Univ, Appl Phys Lab, Columbia, MD USA
[5] Johns Hopkins Univ, Dept Comp Sci, Baltimore, MD USA
[6] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
[7] Hosp Univ Penn, Dept Neurol, 3400 Spruce St, Philadelphia, PA 19104 USA
[8] Stanford Univ, Ctr Cognit & Neurobiol Imaging, Stanford, CA 94305 USA
[9] George Mason Univ, Dept Psychol, Fairfax, VA 22030 USA
来源
GIGASCIENCE | 2017年 / 6卷 / 05期
关键词
Reproducibility; Connectomics; Cloud Computing; MRI; TOOLS;
D O I
10.1093/gigascience/gix013
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Modern technologies are enabling scientists to collect extraordinary amounts of complex and sophisticated data across a huge range of scales like never before. With this onslaught of data, we can allow the focal point to shift from data collection to data analysis. Unfortunately, lack of standardized sharing mechanisms and practices often make reproducing or extending scientific results very difficult. With the creation of data organization structures and tools that drastically improve code portability, we now have the opportunity to design such a framework for communicating extensible scientific discoveries. Our proposed solution leverages these existing technologies and standards, and provides an accessible and extensible model for reproducible research, called 'science in the cloud' (SIC). Exploiting scientific containers, cloud computing, and cloud data services, we show the capability to compute in the cloud and run a web service that enables intimate interaction with the tools and data presented. We hope this model will inspire the community to produce reproducible and, importantly, extensible results that will enable us to collectively accelerate the rate at which scientific breakthroughs are discovered, replicated, and extended.
引用
收藏
页码:1 / 10
页数:10
相关论文
共 39 条
[1]  
[Anonymous], 2015, Building Your Next Big Thing with Google Cloud Platform
[2]  
[Anonymous], 2008, LINUX J
[3]   Enhanced reproducibility of SADI web service workflows with Galaxy and Docker [J].
Aranguren, Mikel Egana ;
Wilkinson, Mark D. .
GIGASCIENCE, 2015, 4
[4]   Bioboxes: standardised containers for interchangeable bioinformatics software [J].
Belmann, Peter ;
Droege, Johannes ;
Bremges, Andreas ;
McHardy, Alice C. ;
Sczyrba, Alexander ;
Barton, Michael D. .
GIGASCIENCE, 2015, 4
[5]  
BREMGES A, 2015, GIGASCIENCE, V0004
[6]  
Brewer E.A., 2015, Proceedings of the Sixth ACM Symposium on Cloud Computing, P167, DOI DOI 10.1145/2806777.2809955
[7]   Microbial Extracellular Enzymes and the Degradation of Natural and Synthetic Polymers in Soil [J].
Burns, Richard G. .
MOLECULAR ENVIRONMENTAL SOIL SCIENCE, 2013, :27-47
[8]  
Craddock RC, 2013, NAT METHODS, V10, P524, DOI [10.1038/nmeth.2482, 10.1038/NMETH.2482]
[9]   LORIS: a web-based data management system for multi-center studies [J].
Das, Samir ;
Zijdenbos, Alex P. ;
Harlap, Jonathan ;
Vins, Dario ;
Evans, Alan C. .
FRONTIERS IN NEUROINFORMATICS, 2012, 5
[10]  
Devisetty U.K., 2016, F1000Research, P5