Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin), and a lincosamide (clindamycin)

被引：63
作者：
Barry, AL [1 ]
Fuchs, PC [1 ]
Brown, SD [1 ]
机构：
[1] Inst Clin Microbiol, Wilsonville, OR 97070 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1998年 / 42卷 / 04期
关键词：
D O I：
10.1128/AAC.42.4.945
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Four different compounds belonging to the macrolide-lincosamide-streptogramin B (MLSb) class of antimicrobial agents were tested against 611 Streptococcus pneumoniae strains. The ketolide (HMR 3647, previously RU66647) and the streptogramin (quinupristin-dalfopristin) were both active against pneumococci with high-level MLSb resistance (clindamycin-resistant strains) as well as those with low-level macrolide resistance (clindamycin-susceptible strains).
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页码：945 / 946
页数：2
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