Cognitive Impairment in Chronic Obstructive Pulmonary Disease (COPD): Possible Utility of Marine Bioactive Compounds

被引：5
作者：
Prinzi, Giulia [1 ]
Santoro, Alessia [1 ]
Lamonaca, Palma [1 ]
Cardaci, Vittorio [2 ]
Fini, Massimo [3 ]
Russo, Patrizia [1 ]
机构：
[1] IRCSS San Raffaele Pisana, Clin & Mol Epidemiol, Via Valcannuta 247, I-00166 Rome, Italy
[2] IRCCS San Raffaele Pisana, Unit Pulm Rehabil, Via Pisana 235, I-00163 Rome, Italy
[3] IRCSS San Raffaele Pisana, Sci Direct, Via Valcannuta 247, I-00166 Rome, Italy
来源：
MARINE DRUGS | 2018年 / 16卷 / 09期
关键词：
COPD; cognitive impairment; management strategy; marine bioactive compound; systems approaches; ALZHEIMERS-DISEASE; DOUBLE-BLIND; ANTICANCER DRUGS; OXIDATIVE STRESS; CELL SENESCENCE; GINKGO-BILOBA; VITAMIN-E; MILD; DEMENTIA; MANAGEMENT;
D O I：
10.3390/md16090313
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Chronic obstructive pulmonary disease (COPD) is characterized by long-term airflow limitation. Early-onset COPD in non-smoker subjects is 60 years and in the elderly is often associated with different comorbidities. Cognitive impairment is one of the most common feature in patients with COPD, and is associated with COPD severity and comorbidities. Cognitive impairment in COPD enhances the assistance requirement in different aspects of daily living, treatment adherence, and effectual self-management.This review describes various bioactive compounds of natural marine sources that modulate different targets shared by both COPD and cognitive impairment and hypothesizes a possible link between these two syndromes.
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页数：20
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