First attempts at prediction of DNA strand-break yields using nanodosimetric data

被引：26

作者：

Garty, G.

Schulte, R.

Shchemelinin, S.

Grosswendt, B.

Leloup, C.

Assaf, G.

Breskin, A.

Chechik, R.

Bashkirov, V.

机构：

[1] Weizmann Inst Sci, Dept Particle Phys, IL-76100 Rehovot, Israel

[2] Loma Linda Univ, Med Ctr, Dept Radiat Med, Loma Linda, CA 92354 USA

[3] Phys Tech Bundesanstalt, D-38116 Braunschweig, Germany

来源：

RADIATION PROTECTION DOSIMETRY | 2006年 / 122卷 / 1-4期

关键词：

D O I：

10.1093/rpd/ncl515

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

We present the first results of our attempts to correlate yields of ionisation clusters in a gas model of DNA and corresponding double-strand break (DSB) yields in irradiated plasmids, using a simple statistical model of DNA lesion formation. Based on the same statistical model, we also provide a comparison of simulated nanodosimetric data for electrons and published DSB yields obtained with the PARTRAC code.

引用

页码：451 / 454

页数：4

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