TUBASTATIN A, A SELECTIVE HISTONE DEACETYLASE-6 INHIBITOR, SUPPRESSES SYNOVIAL INFLAMMATION AND JOINT DESTRUCTION IN A COLLAGEN ANTIBODY-INDUCED ARTHRITIS MOUSE MODEL

被引：0
|
作者：
Lee, J. [1 ]
Jeong, H. [1 ]
Kim, I. Y. [1 ]
Hwang, J. [1 ]
Kim, H. [1 ]
Jeon, C. H. [2 ]
Cha, H. -S. [1 ]
Koh, E. -M. [1 ]
机构：
[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Seoul, South Korea
[2] SoonChunHyang Hosp, Seoul, South Korea
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2014年 / 73卷
关键词：
D O I：
10.1136/annrheumdis-2014-eular.3467
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
FRI0347
引用
收藏
页码：513 / 513
页数：1
相关论文
共 50 条
  • [21] Abnormal cardiomyocyte Ca2+ handling in the Collagen Antibody-Induced Arthritis (CAIA) mouse model for rheumatoid arthritis
    Pironti, G.
    Agalave, A.
    Lanner, J.
    Svensson, C.
    Andersson, D.
    ACTA PHYSIOLOGICA, 2017, 219 : 20 - 21
  • [22] STA-21, a STAT-3 inhibitor, attenuates the development and progression of inflammation in collagen antibody-induced arthritis
    Ahmad, Sheikh Fayaz
    Ansari, Mushtaq Ahmad
    Nadeem, Ahmed
    Zoheir, Khairy M. A.
    Bakheet, Saleh A.
    Alsaad, Abdulaziz M. S.
    Al-Shabanah, Othman A.
    Attia, Sabry M.
    IMMUNOBIOLOGY, 2017, 222 (02) : 206 - 217
  • [23] Novel Bruton's tyrosine kinase inhibitor TAS5315 suppresses the progression of inflammation and joint destruction in rodent collagen-induced arthritis
    Akasaka, Daichi
    Iguchi, Satoru
    Kaneko, Ryusuke
    Yoshiga, Yohei
    Kajiwara, Daisuke
    Nakachi, Yoshinori
    Noma, Naruto
    Tanaka, Kenji
    Shimizu, Atsushi
    Hosoi, Fumihito
    PLOS ONE, 2023, 18 (02):
  • [24] Histone deacetylase 1 is increased in rheumatoid arthritis synovium and promotes synovial cell hyperplasia and synovial inflammation in the collagen-induced arthritis mouse model via the microRNA-124-dependent MARCKS-JAK/STAT axis
    Meng, Q.
    Pan, B.
    Sheng, P.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2021, 39 (05) : 970 - 981
  • [25] An ectosteric tanshinone inhibitor of cathepsin K prevents the progression of joint inflammation and destruction in an arthritis mouse model
    Panwar, Preety
    Bromme, Dieter
    JOURNAL OF BONE AND MINERAL RESEARCH, 2018, 33 : 370 - 370
  • [26] Effects of Mild and Moderate Monoclonal Antibody Dose on Inflammation, Bone Loss, and Activation of the Central Nervous System in a Female Collagen Antibody-induced Arthritis Mouse Model
    Williams, Bonnie
    Lees, Florence
    Tsangari, Helen
    Hutchinson, Mark R.
    Perilli, Egon
    Crotti, Tania N.
    JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 2021, 69 (08) : 511 - 522
  • [27] Histone Deacetylase 6 Inhibitor Suppresses The Inflammation Through MIR17HG In LPS-Induced Macrophages
    Perales, Selene
    Sigamani, Vinoth
    Rajasingh, Sheeja
    Johnson, Rajasingh
    CIRCULATION RESEARCH, 2023, 133
  • [28] Furopyridines, discovery of a novel, potent, and selective class of spleen tyrosine kinase inhibitors with in vivo efficacy in a mouse collagen antibody-induced arthritis model
    Burgdorf, Lars Thore
    Ross, Tatjana
    Deutsch, Carl
    Hodous, Brian
    Potnick, Justin
    Bruns, Lisa
    Grenningloh, Roland
    Ji, Hong
    Camps, Montserrat
    Zimmerli, Simone
    Rohdich, Felix
    Greiner, Hartmut
    Shutes, Adam
    Kuhn, Daniel
    Graedler, Ulrich
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [29] Osteopontin-deficiency suppress joint swelling, chondrocyte apoptosis and joint destruction in antibody-induced rheumatoid arthritis model in mice.
    Yumoto, K
    Ishijima, M
    Rittling, SR
    Tsuji, K
    Tsuchiya, Y
    Kon, S
    Nifuji, A
    Uede, T
    Denhardt, DT
    Noda, M
    JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 : S450 - S450
  • [30] COLLAGEN ANTIBODY-INDUCED ARTHRITIS (CAIA) LEADS TO EVOKED AND ONGOING PERSISTENT PAIN-LIKE BEHAVIOR, BUT TRANSIENT JOINT INFLAMMATION
    Sandor, K.
    Nandakumar, K. S.
    Holmdahl, R.
    Bjornholm, M.
    Tom, R.
    Krook, A.
    Svensson, C., I
    ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 : A32 - A32
12345