K3PO4-Catalyzed Regiospecific Aminobromination of β-Nitrostyrene Derivatives with N-Bromoacetamide as Aminobrominating Agent

被引：51

作者：

Chen, Zhan-Guo

Wang, Yun

Wei, Jun-Fa ^{[1
]}

Zhao, Peng-Fei

Shi, Xian-Ying

机构：

[1] Shaanxi Normal Univ, Sch Chem & Mat Sci, Xian 710062, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 75卷 / 06期

关键词：

CATALYTIC AMINOHALOGENATION REACTION; STEREOSELECTIVE AMINOHALOGENATION; ALPHA; BETA-UNSATURATED KETONES; CINNAMIC ESTERS; HALOGEN SOURCES; IONIC LIQUID; NITROGEN; OLEFINS; ALKENES; NITROALKENES;

D O I：

10.1021/jo9026879

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A very simple, efficient, and regiospecific protocol for aminobromination of a wide scope of beta-nitrostyrene derivatives with N-bromoacetamide (NBA) as nitrogen/bromine sources has been developed by using K3PO4 as catalyst. The reaction proceeded smoothly and cleanly to give the bromoamines in good to excellent yields (78-99%) within 24 h in CH2Cl2 at room temperature Without protection of inert gases. A possible mechanism

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页码：2085 / 2088

页数：4

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