Deformed wing virus

被引：408

作者：

de Miranda, Joachim R. ^{[2
]}

Genersch, Elke ^{[1
]}

机构：

[1] Inst Bee Res, Dept Mol Microbiol & Bee Dis, D-16540 Hohen Neuendorf, Germany

[2] Swedish Univ Agr Sci, Dept Ecol, S-75007 Uppsala, Sweden

来源：

JOURNAL OF INVERTEBRATE PATHOLOGY | 2010年 / 103卷

关键词：

Deformed wing virus (DWV); Genetics; Pathology; Transmission; Virulence; Biological vector; PICORNA-LIKE-VIRUS; HONEYBEES APIS-MELLIFERA; BEE PARALYSIS VIRUS; MOUTH-DISEASE VIRUS; STRAND RNA VIRUSES; VERTICAL-TRANSMISSION; VARROA-JACOBSONI; SACBROOD VIRUS; VIRAL LOAD; STRUCTURAL MOTIFS;

D O I：

10.1016/j.jip.2009.06.012

中图分类号：

Q95 [动物学];

学科分类号：

071002 ;

摘要：

Deformed wing virus (DWV; Iflaviridae) is one of many viruses infecting honeybees and one of the most heavily investigated due to its close association with honeybee colony collapse induced by Varroa destructor. In the absence of V. destructor DWV infection does not result in visible symptoms or any apparent negative impact on host fitness. However, for reasons that are still not fully understood, the transmission of DWV by V. destructor to the developing pupae causes clinical symptoms, including pupal death and adult bees emerging with deformed wings, a bloated, shortened abdomen and discolouration. These bees are not viable and die soon after emergence. In this review we will summarize the historical and recent data on DWV and its relatives, covering the genetics, pathobiology, and transmission of this important viral honeybee pathogen, and discuss these within the wider theoretical concepts relating to the genetic variability and population structure of RNA viruses, the evolution of virulence and the development of disease symptoms. (C) 2009 Elsevier Inc. All rights reserved

引用

页码：S48 / S61

页数：14

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