Intestinal Microbiota and Kidney Diseases

被引：4
|
作者：
Xie, Ao [1 ]
Sheng, Jie [1 ]
Zheng, Feng [1 ]
机构：
[1] Dalian Med Univ, Hosp 2, Adv Inst Med Sci, Dalian 116044, Liaoning, Peoples R China
来源：
CHINESE JOURNAL OF INTEGRATIVE MEDICINE | 2018年 / 24卷 / 06期
基金：
中国国家自然科学基金;
关键词：
microbiota; IgA nephropathy; chronic kidney disease; uremia; IGA NEPHROPATHY; GUT; IMMUNITY;
D O I：
10.1007/s11655-017-2927-5
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Kidney diseases are common and the incidence rate is increasing. Gut microbiota is involved in metabolic and immune regulation of the host. Genetic, alimentary and environmental disease factors may change gut flora and increase opportunistic and pathogenic bacteria, contributing to immune or non-immune mediated kidney diseases including IgA nephropathy and diabetic nephropathy. Additionally, bacterial metabolites may be a source of uremic toxins. Thus, identification of diversity, composition, and metabolic and immunologic features of gut bacteria in chronic kidney diseases may help understand pathogenetic mechanism and develop therapy for diseases.
引用
收藏
页码：406 / 408
页数：3
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