Hepatitis C virus infection from the perspective of heterologous immunity

被引：19

作者：

Cornberg, Markus ^{[1
,2
]}

Wedemeyer, Heiner ^{[1
]}

机构：

[1] Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, D-30623 Hannover, Germany

[2] Partner Site Hannover Braunschweig, German Ctr Infect Res DZIF, Hannover, Germany

来源：

CURRENT OPINION IN VIROLOGY | 2016年 / 16卷

关键词：

CROSS-GENOTYPE-REACTIVITY; ORIGINAL ANTIGENIC SIN; EARLY BCG VACCINATION; PHENOTYPE T-CELLS; INFLUENZA-VIRUS; EXTRAHEPATIC MANIFESTATIONS; MEMORY; RESPONSES; CLEARANCE; EPITOPE;

D O I：

10.1016/j.coviro.2016.01.005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Heterologous immunity can impact the natural course of subsequent infections by different mechanisms such as polarization of TH1/TH2 responses, induction of cytokines and T cell cross-reactivity. In the case of hepatitis C virus (HCV) infection, heterologous immunity helps to explain the high variability in clinical outcomes. This review discusses how other infections can alter the natural course of hepatitis C and how HCV infection influence unrelated infections.

引用

页码：41 / 48

页数：8

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