The Proteome in Balance

被引：42

作者：

Hutt, Darren ^{[1
]}

Balch, William E. ^{[1
,2
,3
]}

机构：

[1] Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Dept Physiol Chem, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

[3] Scripps Res Inst, Inst Childhood & Neglected Dis, La Jolla, CA 92037 USA

来源：

SCIENCE | 2010年 / 329卷 / 5993期

关键词：

CYSTIC-FIBROSIS; CHAPERONE; PROTEOSTASIS; DISEASE; CFTR;

D O I：

10.1126/science.1194160

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：766 / 767

页数：2

共 16 条

[1] Adapting proteostasis for disease intervention [J].

Balch, William E. ;

Morimoto, Richard I. ;

Dillin, Andrew ;

Kelly, Jeffery W. .

SCIENCE, 2008, 319 (5865) :916-919

[2] The role of molecular chaperones in human misfolding diseases [J].

Broadley, Sarah A. ;

Hartl, F. Ulrich .

FEBS LETTERS, 2009, 583 (16) :2647-2653

[3] Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance [J].

Geller, Ron ;

Vignuzzi, Marco ;

Andino, Raul ;

Frydman, Judith .

GENES & DEVELOPMENT, 2007, 21 (02) :195-205

[4] Converging concepts of protein folding in vitro and in vivo [J].

Hartl, F. Ulrich ;

Hayer-Hartl, Manajit .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2009, 16 (06) :574-581

[5] The proteostasis boundary in misfolding diseases of membrane traffic [J].

Hutt, Darren M. ;

Powers, Evan T. ;

Balch, William E. .

FEBS LETTERS, 2009, 583 (16) :2639-2646

[6] Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging [J].

Morimoto, Richard I. .

GENES & DEVELOPMENT, 2008, 22 (11) :1427-1438

[7] Protein Homeostasis and Aging: Taking Care of Proteins From the Cradle to the Grave [J].

Morimoto, Richard I. ;

Cuervo, Ana M. .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2009, 64 (02) :167-170

[8] Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane [J].

Okiyoneda, Tsukasa ;

Barriere, Herve ;

Bagdany, Miklos ;

Rabeh, Wael M. ;

Du, Kai ;

Hoehfeld, Joerg ;

Young, Jason C. ;

Lukacs, Gergely L. .

SCIENCE, 2010, 329 (5993) :805-810

[9] Signals of youth: endocrine regulation of aging in Caenorhabditis elegans [J].

Panowski, Siler H. ;

Dillin, Andrew .

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2009, 20 (06) :259-264

[10] Biological and Chemical Approaches to Diseases of Proteostasis Deficiency [J].

Powers, Evan T. ;

Morimoto, Richard I. ;

Dillin, Andrew ;

Kelly, Jeffery W. ;

Balch, William E. .

ANNUAL REVIEW OF BIOCHEMISTRY, 2009, 78 :959-991

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