Anticoagulation in Critically Ill Adults during Extracorporeal Circulation

被引：11

作者：

Buchtele, Nina ^{[1
]}

Staudinger, Thomas ^{[1
]}

Schaefer, Anne-Kristin ^{[2
]}

Boegl, Magdalena Sophie ^{[3
]}

Schoergenhofer, Christian ^{[4
]}

Schwameis, Michael ^{[3
]}

机构：

[1] Med Univ Vienna, Dept Med 1, Wahringer Gurtel 18-20, A-1090 Vienna, Austria

[2] Med Univ Vienna, Dept Surg, Div Cardiac Surg, Vienna, Austria

[3] Med Univ Vienna, Dept Emergency Med, Vienna, Austria

[4] Med Univ Vienna, Dept Clin Pharmacol, Vienna, Austria

来源：

HAMOSTASEOLOGIE | 2021年 / 41卷 / 04期

关键词：

anticoagulants; blood coagulation tests; continuous renal replacement therapy; extracorporeal membrane oxygenation; heart-assist devices; VENTRICULAR ASSIST DEVICE; MOLECULAR-WEIGHT HEPARIN; MEMBRANE-OXYGENATION; UNFRACTIONATED HEPARIN; CLOTTING TIME; LIFE-SUPPORT; BIVALIRUDIN; SAFETY; HEMODIALYSIS; MANAGEMENT;

D O I：

10.1055/a-1389-8216

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Extracorporeal circuits including renal replacement therapy, extracorporealmembrane oxygenation, and ventricular assist devices are increasingly used in critically ill patients. The need for anticoagulation to provide circuit patency and avoid thrombosis remains a challenging task for treating physicians. In the presence of overall low scientific evidence concerning the optimal anticoagulants, monitoring tests, and therapeutic target ranges, recommendations are largely expert opinions and most centers use individual " in-house" anticoagulation protocols. This review gives a practical view on current concepts of anticoagulation strategies in patients with extracorporeal assist devices.

引用

页码：294 / 306

页数：13

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