Electronic tuning of the PNNP ligand for the asymmetric cyclopropanation of olefins catalysed by [RuCl(PNNP)]

被引：49

作者：

Bonaccorsi, C ^{[1
]}

Bachmann, S ^{[1
]}

Mezzetti, A ^{[1
]}

机构：

[1] ETH Honggerberg, Swiss Fed Inst Technol, Dept Chem, CH-8093 Zurich, Switzerland

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(03)00033-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Cationic ruthenium complexes of the type [RuCl(L)(PNNP)](+) (L=OEt2, OH2), where PNNP is the CF3-subsituted PNNP ligand N,N'-bis[o-(bis(4-trifluoromethylphenyl)phosphino)benzylidene]-(IS,2S)-diaminocyclohexane 1b, catalyse the asymmetric cyclopropanation of styrene, alpha-Me-styrene, and I-octene with ethyl diazoacetate. These complexes are more active and give higher cis- and enantioselectivities than their analogues containing the unsubstituted ligand la. Thus, [RuCl(OEt2)(1b)]PF6 cyclopropanates alpha-Me-styrene with 85% cis selectivity and 86% ee in 94% isolated yield. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：845 / 854

页数：10

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