Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic

被引：72

作者：

Saunte, D. M. L. ^{[1
,2
,3
]}

Pereiro-Ferreiros, M. ^{[1
,4
]}

Rodriguez-Cerdeira, C. ^{[1
,5
,6
]}

Sergeev, A. Y. ^{[1
,7
]}

Arabatzis, M. ^{[1
,8
]}

Prohic, A. ^{[1
,9
]}

Piraccini, B. M. ^{[1
,10
]}

Lecerf, P. ^{[1
,11
]}

Nenoff, P. ^{[1
,12
]}

Kotrekhova, L. P. ^{[13
]}

Bosshard, P. P. ^{[14
,15
]}

Padovese, V ^{[16
]}

Szepietowski, J. C. ^{[1
,17
]}

Sigurgeirsson, B. ^{[1
,18
]}

Nowicki, R. J. ^{[1
,19
]}

Schmid-Grendelmeier, P. ^{[1
,15
,20
]}

Hay, R. J. ^{[1
,21
]}

机构：

[1] European Acad Dermatol & Venereol Task Force Myco, Lugano, Switzerland

[2] Zealand Univ Hosp, Dept Dermatol, Roskilde, Denmark

[3] Univ Copenhagen, Fac Hlth Sci, Dept Clin Med, Copenhagen, Denmark

[4] Univ Santiago de Compostela, Fac Med, Dermatol, La Coruna, Spain

[5] Meixoeiro Hosp, Dept Dermatol, Vigo, Spain

[6] Univ Vigo, Vigo, Spain

[7] Sechenov Univ, Dept Clin Immunol, Moscow, Russia

[8] Aristotle Univ Thessaloniki, Med Sch, Dept Dermatol, Thessaloniki, Greece

[9] Univ Sarajevo, Sarajevo Med Sch, Dept Dermatovenereol, Sch Sci & Technol, Sarajevo, Bosnia & Herceg

[10] Univ Bologna, Dermatol IRCCS Policlin St Orsola, Dept Expt Diagnost & Specialty Med DIMES, Alma Mater Studiorum, Bologna, Italy

[11] Univ Libre Bruxelles, Dept Dermatol, Univ Hosp Brugmann & St Pierre, Brussels, Belgium

[12] Lab Med Microbiol, Molbis, Germany

[13] North Western State Med Univ, Dept Dermatovenereol, St Petersburg, Russia

[14] Univ Zurich, Univ Hosp Zurich, Dept Dermatol, Zurich, Switzerland

[15] Univ Zurich, Med Fac, Zurich, Switzerland

[16] Mater Dei Hosp, Dept Dermatol & Venereol, Genitourinary Clin, Msida, Malta

[17] Wroclaw Med Univ, Dept Dermatol Venereol & Allergol, Wroclaw, Poland

[18] Univ Iceland, Fac Med, Dept Dermatol, Reykjavik, Iceland

[19] Med Univ Gdansk, Dept Dermatol Venereol & Allergol, Gdansk, Poland

[20] Univ Zurich, Univ Hosp Zurich, Dept Dermatol, Allergy Unit, Zurich, Switzerland

[21] Kings Coll London, St Johns Inst Dermatol, London, England

来源：

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY | 2021年 / 35卷 / 07期

关键词：

D O I：

10.1111/jdv.17241

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe. Objectives To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe. Methods A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe. Results Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases. Conclusions This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.

引用

页码：1582 / 1586

页数：5

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