Mixture toxicity of four commonly used pesticides at different effect levels to the epigeic earthworm, Eisenia fetida

被引：50

作者：

Yang, Guiling ^{[1
,2
]}

Chen, Chen ^{[1
]}

Wang, Yanhua ^{[2
]}

Peng, Qi ^{[2
]}

Zhao, Huiyu ^{[2
]}

Guo, Dongmei ^{[1
]}

Wang, Qiang ^{[2
]}

Qian, Yongzhong ^{[1
]}

机构：

[1] Chinese Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Key Lab Agroprod Qual & Safety, Minist Agr, Beijing 100081, Peoples R China

[2] Zhejiang Acad Agr Sci, State Key Lab Breeding Base Zhejiang Sustainable, Lab Hangzhou Risk Assessment Agr Prod,Minist Agr, Key Lab Pesticide Residue Detect,Minist Agr,Inst, Hangzhou 310021, Zhejiang, Peoples R China

来源：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY | 2017年 / 142卷

关键词：

Soil invertebrates; Terrestrial ecotoxicology; Mixture toxicity; Pesticide; Combination Index; CHIRONOMUS-TENTANS DIPTERA; ASSESSING JOINT TOXICITY; TOXICOLOGICAL INTERACTIONS; CAENORHABDITIS-ELEGANS; FATHEAD MINNOWS; RISK-ASSESSMENT; DAPHNIA-MAGNA; BIOCIDES; END-POINT; INSECTICIDES;

D O I：

10.1016/j.ecoenv.2017.03.037

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

As commonly used pesticides, chlorpyrifos (CPF), fenobucarb (FEN), clothianidin (CLO) and acetochlor (ACE) are widely applied on crops worldwide. In this study, the combined toxicities of their binary, ternary and quaternary mixtures were evaluated using the earthworm Eisenia fetida as test organism. Mixture toxicities were studied using the combination index (CI) method and visualized by isobolograms, and then data were compared with traditional concentration addition (CA) and independent action (IA) models. Two binary mixtures of CPF +FEN and FEN +ACE, two ternary mixtures of CPF + CLO + FEN and CPF +FEN+ ACE, and quaternary mixture of CPF +FEN + ACE+ CLO exhibited a clear synergistic effect. The CI method was compared with the classical models of CA and IA, indicating that the CI method could accurately predict the combined toxicities of the chemicals. The results indicated that it was difficult to predict combined effects of these pesticides from mode of action alone because of existence of complicated synergistic and antagonistic responses. More attention should be paid to the potential synergistic effects of chemicals interactions, which might cause serious ecological problems.

引用

页码：29 / 39

页数：11

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