Impact of diet on human gut microbiome and disease risk

被引:26
作者
Mansour, S. R. [1 ]
Moustafa, M. A. A. [2 ]
Saad, B. M. [1 ]
Hamed, R. [1 ]
Moustafa, A. -R. A. [1 ]
机构
[1] Suez Canal Univ, Dept Bot, Fac Sci, Ismailia, Egypt
[2] 6 October Univ, Fac Med, 6 October, Egypt
关键词
Diet; diversity of microbial gut; gut microbiome; human health; metabolic disorder; unbalanced diet; BRAIN AXIS; BACTERIA; CANCER; BINDING;
D O I
10.1016/j.nmni.2021.100845
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The gut microbiome of humans comprises a diverse group of trillions of microorganisms including symbiotic organisms, opportunistic pathogens and commensal organisms. This microbiota plays a major role in digesting food; it also helps with absorbing and synthesizing some nutrients and releases their metabolites, which may deliver a variety of growth-promoting and growth-inhibiting factors that influence human health either directly or indirectly. The balance between microbial species, especially those responsible for the fermentation of different substrates within the microbial community, which are in the majority, depends on daily diet. Therefore, an unbalanced diet may lead to the progression and development of human diseases. These include metabolic and inflammatory disorders, cancer and depression, as well as infant health and longevity. We provide an overview of the effect of diet on the human microbiome and assess the related risk of disease development. (c) 2021 The Authors. Published by Elsevier Ltd.
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页数:7
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