Rare EBV-associated B cell neoplasms of the gastrointestinal tract

被引：8
作者：
Volaric, Ashley K. [1 ]
Singh, Kunwar [1 ]
Gru, Alejandro A. [2 ]
机构：
[1] Stanford Med, Dept Pathol, Stanford, CA USA
[2] Univ Virginia, Dept Pathol, Charlottesville, VA 22903 USA
来源：
SEMINARS IN DIAGNOSTIC PATHOLOGY | 2021年 / 38卷 / 04期
关键词：
EBV; Lymphoma; GI tract; HHV-8; EPSTEIN-BARR-VIRUS; PRIMARY-EFFUSION-LYMPHOMA; SARCOMA-ASSOCIATED HERPESVIRUS; POSITIVE MUCOCUTANEOUS ULCER; HIV-INFECTED PATIENTS; GENE-EXPRESSION; LYMPHOPROLIFERATIVE DISORDERS; EXTRACAVITARY/SOLID VARIANT; BURKITTS-LYMPHOMA; UPDATE;
D O I：
10.1053/j.semdp.2021.04.004
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
EBV-driven B cell neoplasms can rarely present as an extranodal mass in the gastrointestinal tract and can be missed, even by experienced pathologists, because of this uncommon presentation. A selection of these neoplasms, namely EBV-positive diffuse large B cell lymphoma, not otherwise specified (DLBCL NOS), EBV-positive mucocutaneous ulcer (EBV MCU), extracavitary primary effusion lymphoma (EPEL), and EBV-positive Burkitt lymphoma, will be discussed in the present review. Besides the common thread of EBV positivity, these lymphoproliferative disorders arise in unique clinical settings that are often associated with immunodeficiency, immunosuppression or immunosenescence and can present as solitary masses albeit rarely, within the gastrointestinal tract.
引用
收藏
页码：38 / 45
页数：8
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