Achalasia

被引：28

作者：

Islam, Saleem ^{[1
]}

机构：

[1] Univ Florida, Coll Med, Div Pediat Surg, 1600 SW Archer Rd,POB 100119, Gainesville, FL 32610 USA

来源：

SEMINARS IN PEDIATRIC SURGERY | 2017年 / 26卷 / 02期

关键词：

Esophageal achalasia; Heller myotomy; Fundoplication; Manometry; Endoscopic therapy; LAPAROSCOPIC HELLER MYOTOMY; PERORAL ENDOSCOPIC MYOTOMY; ESOPHAGEAL MOTILITY DISORDERS; IDIOPATHIC ACHALASIA; PEDIATRIC ACHALASIA; DOR FUNDOPLICATION; PNEUMATIC DILATION; CHILDHOOD ACHALASIA; BOTULINUM TOXIN; CHILDREN;

D O I：

10.1053/j.sempedsurg.2017.02.001

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Achalasia is a rare neurogenic motility disorder of the esophagus, occurring in approximately Oil cases per 100,000 children. The combination of problems (aperistalsis, hypertensive lower esophageal sphincter (LES), and lack of receptive LES relaxation) results in patients having symptoms of progressive dysphagia, weight loss, and regurgitation. Treatment modalities have evolved over the past few decades from balloon dilation and botulinum toxin injection to laparoscopic Heller myotomy and endoscopic myotomy. Most data on achalasia management is extrapolated to children from adult experience. This article describes understanding of the pathogenesis and discusses newer therapeutic techniques as well as controversies in management. (C) 2017 Elsevier Inc. All rights reserved.

引用

页码：116 / 120

页数：5

共 72 条

[1] Evaluation of the response to treatment in patients with idiopathic achalasia by the timed barium esophagogram: results from a randomized clinical trial [J].

Andersson, M. ;

Lundell, L. ;

Kostic, S. ;

Ruth, M. ;

Lonroth, H. ;

Kjellin, A. ;

Hellstrom, M. .

DISEASES OF THE ESOPHAGUS, 2009, 22 (03) :264-273

[2] Laparoscopic extended cardiomyotomy in children: an effective procedure for the treatment of esophageal achalasia [J].

Aoun Tannuri, Ana Cristina ;

Tannuri, Uenis ;

Prieto Velhote, Manoel Carlos ;

Pinto Romao, Rodrigo Luiz .

JOURNAL OF PEDIATRIC SURGERY, 2010, 45 (07) :1463-1466

[3] Minimally invasive Heller's myotomy in children: safe and effective [J].

Askegard-Giesmann, Johanna R. ;

Grams, Jayleen M. ;

Hanna, Angela M. ;

Iqbal, Corey W. ;

Teh, Swee ;

Moir, Christopher R. .

JOURNAL OF PEDIATRIC SURGERY, 2009, 44 (05) :909-911

[4] Per-oral endoscopic myotomy, 1000 cases later: pearls, pitfalls, and practical considerations [J].

Bechara, Robert ;

Onimaru, Manabu ;

Ikeda, Haru ;

Inoue, Haruhiro .

GASTROINTESTINAL ENDOSCOPY, 2016, 84 (02) :330-338

[5] Achalasia [J].

Boeckxstaens, Guy E. ;

Zaninotto, Giovanni ;

Richter, Joel E. .

LANCET, 2014, 383 (9911) :83-93

[6] Pneumatic Dilation versus Laparoscopic Heller's Myotomy for Idiopathic Achalasia [J].

Boeckxstaens, Guy E. ;

Annese, Vito ;

des Varannes, Stanislas Bruley ;

Chaussade, Stanislas ;

Costantini, Mario ;

Cuttitta, Antonello ;

Ignasi Elizalde, J. ;

Fumagalli, Uberto ;

Gaudric, Marianne ;

Rohof, Wout O. ;

Smout, Andre J. ;

Tack, Jan ;

Zwinderman, Aeilko H. ;

Zaninotto, Giovanni ;

Busch, Olivier R. .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (19) :1807-1816

[7] Effects of sildenafil on esophageal motility of patients with idiopathic achalasia [J].

Bortolotti, M ;

Mari, C ;

Lopilato, C ;

Porrazzo, G ;

Miglioli, M .

GASTROENTEROLOGY, 2000, 118 (02) :253-257

[8] White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies [J].

Burns, Alan J. ;

Goldstein, Allan M. ;

Newgreen, Donald F. ;

Stamp, Lincon ;

Schaefer, Karl-Herbert ;

Metzger, Marco ;

Hotta, Ryo ;

Young, Heather M. ;

Andrews, Peter W. ;

Thapar, Nikhil ;

Belkind-Gerson, Jaime ;

Bondurand, Nadege ;

Bornstein, Joel C. ;

Chan, Wood Yee ;

Cheah, Kathryn ;

Gershon, Michael D. ;

Heuckeroth, Robert O. ;

Hofstra, Robert M. W. ;

Just, Lothar ;

Kapur, Raj P. ;

King, Sebastian K. ;

McCann, Conor J. ;

Nagy, Nandor ;

Ngan, Elly ;

Obermayr, Florian ;

Pachnis, Vassilis ;

Pasricha, Pankaj J. ;

Sham, Mai Har ;

Tam, Paul ;

Vanden Berghe, Pieter .

DEVELOPMENTAL BIOLOGY, 2016, 417 (02) :229-251

[9] Treatment of esophageal achalasia in children: Today and tomorrow [J].

Caldaro, Tamara ;

Familiari, Pietro ;

Romeo, Erminia Francesca ;

Gigante, Giovanni ;

Marchese, Michele ;

Contini, Anna Chiara Iolanda ;

di Abriola, Giovanni Federici ;

Cucchiara, Salvatore ;

De Angelis, Paola ;

Torroni, Filippo ;

Dall'Oglio, Luigi ;

Costamagna, Guido .

JOURNAL OF PEDIATRIC SURGERY, 2015, 50 (05) :726-730

[10] Endoscopic and Surgical Treatments for Achalasia A Systematic Review and Meta-Analysis [J].

Campos, Guilherme M. ;

Vittinghoff, Eric ;

Rabl, Charlotte ;

Takata, Mark ;

Gadenstaetter, Michael ;

Lin, Feng ;

Ciovica, Ruxandra .

ANNALS OF SURGERY, 2009, 249 (01) :45-57

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