TFE3, HSP47, and CREB3 Pathways of the Mammalian Golgi Stress Response

被引:77
作者
Taniguchi, Mai [1 ]
Yoshida, Hiderou [1 ]
机构
[1] Univ Hyogo, Dept Mol Biochem, Grad Sch Life Sci, Harima, Hyogo 6781297, Japan
关键词
TFE3; MLX; HSP47; CREB3; organelle autoregulation; ENDOPLASMIC-RETICULUM STRESS; UNFOLDED PROTEIN RESPONSE; ER-STRESS; TRANSCRIPTION FACTOR; BINDING; IDENTIFICATION; BIOSYNTHESIS; DISSOCIATION; EXPRESSION; NETWORK;
D O I
10.1247/csf.16023
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The capacity of each organelle in eukaryotic cells is tightly regulated in accordance with cellular demands by specific regulatory systems, which are generically termed organelle autoregulation. The Golgi stress response is one of the systems of organelle autoregulation and it augments the capacity of Golgi function if this becomes insufficient (Golgi stress). Recently, several pathways of the mammalian Golgi stress response have been identified, specifically the TFE3, HSP47, and CREB3 pathways. This review summarizes the essential parts of the Golgi stress response from the perspective of the organelle autoregulation.
引用
收藏
页码:27 / 36
页数:10
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