Highly selective catalyst-directed pathways to dihydropyrroles from vinyldiazoacetates and imines

被引：119

作者：

Doyle, MP ^{[1
]}

Yan, M ^{[1
]}

Hu, WH ^{[1
]}

Gronenberg, LS ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 16期

关键词：

D O I：

10.1021/ja029745q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Copper-catalyzed reactions of vinyldiazoacetates with imines occur via a pathway in which the activated imine undergoes electrophilic addition to the vinyldiazo compound, whereas reactions catalyzed by rhodium(II) proceed through a metal carbene to an intermediate iminium-ylide. Both pathways exhibit high stereoselectivities. Copyright © 2003 American Chemical Society.

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页码：4692 / 4693

页数：2

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