T-cell co-stimulatory molecules: novel targets for the treatment of allergic airway disease

被引：14

作者：

Beier, K. C. ^{[1
]}

Kallinich, T. ^{[1
]}

Hamelmann, E. ^{[1
]}

机构：

[1] Univ Med Berlin, Charite, Dept Paediat Pneumol & Immunol, D-13353 Berlin, Germany

来源：

EUROPEAN RESPIRATORY JOURNAL | 2007年 / 30卷 / 02期

关键词：

allergic airway disease; asthma; co-stimulation; T-cells; therapeutic targets;

D O I：

10.1183/09031936.00094406

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The first two articles in this series discussed the fundamental concept of T-cell co-stimulation as a key event in the induction of any immune response, in addition to reviewing the current data on the role of co-stimulatory molecules for the induction and progression of allergic airway diseases. Based on these considerations, this final edition will delineate and discuss novel strategies for the prevention and/or therapy of allergic diseases based upon the modulation of costimulation.

引用

页码：383 / 390

页数：8

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