Consistent micro, macro and state-based population modelling

被引:20
作者
Gustafsson, Leif [1 ]
Sternad, Mikael [1 ]
机构
[1] Uppsala Univ, Dept Sci & Engn, SE-75121 Uppsala, Sweden
关键词
Model comparison; Poisson Simulation; Population model; Simulation methodology; Stochastic integration; Stochastic time handling; POISSON SIMULATION;
D O I
10.1016/j.mbs.2010.02.003
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A population system can be modelled using a micro model focusing on the individual entities, a macro model where the entities are aggregated into compartments, or a state-based model where each possible discrete state in which the system can exist is represented. However, the concepts, building blocks, procedural mechanisms and the time handling for these approaches are very different. For the results and conclusions from studies based on micro, macro and state-based models to be consistent (contradiction-free), a number of modelling issues must be understood and appropriate modelling procedures be applied. This paper presents a uniform approach to micro, macro and state-based population modelling so that these different types of models produce consistent results and conclusions. In particular, we demonstrate the procedures (distribution, attribute and combinatorial expansions) necessary to keep these three types of models consistent. We also show that the different time handling methods usually used in micro, macro and state-based models can be regarded as different integration methods that can be applied to any of these modelling categories. The result is free choice in selecting the modelling approach and the time handling method most appropriate for the study without distorting the results and conclusions. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码:94 / 107
页数:14
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