Highly Fluorescent and Photostable Polymeric Nanofibers as Scaffolds for Cell Interfacing and Long-Term Tracking

被引：20

作者：

Diao, Hua Jia ^{[1
]}

Wang, Kai ^{[1
]}

Long, Hong Yan ^{[1
]}

Wang, Mingfeng ^{[1
]}

Chew, Sing Yan ^{[1
,2
]}

机构：

[1] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637459, Singapore

[2] Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore 636921, Singapore

来源：

ADVANCED HEALTHCARE MATERIALS | 2016年 / 5卷 / 05期

基金：

英国医学研究理事会;

关键词：

SIRNA DELIVERY; ENGINEERED NANOFIBERS; PRECURSOR CELLS; STEM-CELLS; DIFFERENTIATION; MYELINATION; MATURATION; REMYELINATION; CULTURE; IMAGE;

D O I：

10.1002/adhm.201500693

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Highly fluorescent polymeric nanofibers fabricated via electrospinning of PCL-DPP-PCL (photostable polycaprolactonesdi-(thiophene-2-yl)-diketopyrrolopyrrolephotostable polycaprolactones) and commercial PCL mixture show superior photostability and cytocompatibility for long-term tracking of cell-substrate inter action. As a proof of concept, these PCL-DPP-PCL nanofi bers enable clear visualization of intricate cell-substrate interactions such as oligodendrocyte myelination.

引用

页码：529 / 533

页数：5

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