Synthesis and Reactivity of Rhodium(II) N-Triflyl Azavinyl Carbenes

被引：183

作者：

Grimster, Neil ^{[1
]}

Zhang, Li ^{[1
]}

Fokin, Valery V. ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 08期

基金：

美国国家卫生研究院;

关键词：

INSERTION; CYCLOPROPANATION;

D O I：

10.1021/ja910187s

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Highly reactive rhodium(II) N-trifluoromethylsulfonyl azavinyl carbenes are formed in situ from NH-1,2,3-triazoles, triflic anhydride, and rhodium carboxylates. They rapidly and selectively react with olefins, providing cyclopropane carboxaldehydes and 2,3-dihydropyrroles in generally excellent yields and high enantio- and diastereoselectivity.

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收藏

页码：2510 / +

页数：3

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