Overview of the Korean Longitudinal Study on Cognitive Aging and Dementia

被引：83

作者：

Han, Ji Won ^{[1
]}

Kim, Tae Hui ^{[2
]}

Kwak, Kyung Phil ^{[3
]}

Kim, Kayoung ^{[4
]}

Kim, Bong Jo ^{[5
]}

Kim, Shin Gyeom ^{[6
]}

Kim, Jeong Lan ^{[7
]}

Kim, Tae Hyun ^{[1
]}

Moon, Seok Woo ^{[8
]}

Park, Jae Young ^{[1
]}

Park, Joon Hyuk ^{[9
]}

Byun, Seonjeong ^{[1
]}

Suh, Seung Wan ^{[1
]}

Seo, Ji Young ^{[10
]}

So, Yoonseop ^{[1
]}

Ryu, Seung-Ho ^{[11
]}

Youn, Jong Chul ^{[12
]}

Lee, Kyoung Hwan ^{[13
]}

Lee, Dong Young ^{[14
,15
]}

Lee, Dong Woo ^{[16
]}

Lee, Seok Bum ^{[17
]}

Lee, Jung Jae ^{[17
]}

Lee, Ju Ri ^{[1
]}

Jeong, Hyeon ^{[1
]}

Jeong, Hyun-Ghang ^{[18
]}

Jhoo, Jin Hyeong ^{[19
]}

Han, Kyuhee ^{[1
]}

Hong, Jong Woo ^{[1
]}

Kim, Ki Woong ^{[1
,15
,20
]}

机构：

[1] Seoul Natl Univ, Bundang Hosp, Dept Neuropsychiat, Seongnam, South Korea

[2] Yonsei Univ, Wonju Severance Christian Hosp, Dept Psychiat, Wonju, South Korea

[3] Dongguk Univ, Gyeongju Hosp, Dept Psychiat, Gyeongju, South Korea

[4] Natl Ctr Mental Hlth, Dept Psychiat, Seoul, South Korea

[5] Gyeongsang Natl Univ, Sch Med, Dept Psychiat, Jinju, South Korea

[6] Soonchunhyang Univ, Bucheon Hosp, Dept Neuropsychiat, Bucheon, South Korea

[7] Chungnam Natl Univ, Sch Med, Dept Psychiat, Daejeon, South Korea

[8] Konkuk Univ, Chungju Hosp, Sch Med, Dept Psychiat, Chungju, South Korea

[9] Jeju Natl Univ Hosp, Dept Neuropsychiat, Jeju, South Korea

[10] Changwon Gyeongsang Natl Univ Hosp, Dept Neuropsychiat, Chang Won, South Korea

[11] Konkuk Univ, Med Ctr, Sch Med, Dept Psychiat, Seoul, South Korea

[12] Kyunggi Prov Hosp Elderly, Dept Neuropsychiat, Yongin, South Korea

[13] Bongseng Mem Hosp, Dept Psychiat, Busan, South Korea

[14] Seoul Natl Univ Hosp, Dept Neuropsychiat, Seoul, South Korea

[15] Seoul Natl Univ, Coll Med, Dept Psychiat, Seoul, South Korea

[16] Inje Univ, Sanggye Paik Hosp, Dept Neuropsychiat, Seoul, South Korea

[17] Dankook Univ Hosp, Dept Psychiat, Cheonan, South Korea

[18] Korea Univ, Coll Med, Guro Hosp, Dept Psychiat, Seoul, South Korea

[19] Kangwon Natl Univ, Sch Med, Dept Psychiat, Chunchon, South Korea

[20] Seoul Natl Univ, Coll Nat Sci, Dept Brain & Cognit Sci, Seoul, South Korea

来源：

PSYCHIATRY INVESTIGATION | 2018年 / 15卷 / 08期

关键词：

Community; Multicenter; Longitudinal; Prospective; Cohort study; Cognitive ageing; Dementia; Mild cognitive impairment; Korea; ALZHEIMERS-DISEASE; PATIENT DEPENDENCE; ASSESSMENT BATTERY; RATING-SCALE; IMPAIRMENT; INSTRUMENT; CONSORTIUM; RISK; QUESTIONNAIRE; INVENTORY;

D O I：

10.30773/pi.2018.06.02

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective Due to an unprecedented rate of population aging, South Korea is facing a dementia epidemic. For this reason, the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) was launched in 2009 with support from the Korean Health Industry Development Institute to investigate the epidemiology, biopsychosocial risk factors, and outcomes of dementia and dementia-related conditions. Methods The KLOSCAD is the first nationwide multi-center population-based prospective cohort study. In October 2010, 12,694 individuals were randomly sampled from residents aged 60 years or older who lived in 13 districts across South Korea. In the baseline assessment, which was conducted from November 2010 through October 2012, 6,818 (53.7%) individuals participated. Follow-up assessments have been conducted every two years, with the first follow-up assessment conducted between November 2012 and October 2014, and the second between November 2014 and October 2016. The third is now in progress, and will span from November 2016 to October 2018. Diagnosis of cognitive disorders, neuropsychological battery, behavioral and psychological symptoms of dementia, activities of daily living, physical and neurologic examination and laboratory tests, life styles, quality of life, and identification of death were evaluated in each assessment. Results The cumulative drop-out rate at the second follow-up assessment was 38.7%. Dementia and mild cognitive impairment were 5.0% and 27.0%, respectively. Conclusion The KLOSCAD may provide strong scientific evidence for advancing the fight against dementia both in Korea and globally.

引用

页码：767 / 774

页数：8

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