Conversion of naringenin and hesperetin by heterogeneous catalytic Baeyer-Villiger reaction into lactones exhibiting apoptotic activity

被引：54
作者：
Bernini, R [1 ]
Mincione, E [1 ]
Cortese, M [1 ]
Saladino, R [1 ]
Gualandi, G [1 ]
Belfiore, MC [1 ]
机构：
[1] Univ Tuscia, Dipartimento ABAC, I-01100 Viterbo, Italy
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 26期
关键词：
naringenin; hesperetin; Baeyer-Villiger reaction; lietero-eneous catalysis;
D O I：
10.1016/S0040-4039(03)01139-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Naringenin and hesperetin were converted into the corresponding lactones by hydrogen peroxide activated by poly(4-vinylpiridine)-supported methyltrioxorhenium in t-butanol, an environmentally friendly catalytic system. The products Showed a marked apoptotic activity in the genetic tests. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：4823 / 4825
页数：3
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