Cost-effectiveness of a wetting method intervention to reduce cassava cyanide-related cognitive impairment in children

被引：3

作者：

Chen, Chen ^{[1
]}

Kashala-Abotnes, Esperance ^{[2
]}

Banea Mayambu, Jean-Pierre ^{[3
]}

Mumba Ngoyi, Dieudonne ^{[4
]}

Tshala-Katumbay, Desire ^{[5
,6
]}

Mukeba, Daniel ^{[6
]}

Kunyu, Marcel ^{[6
]}

Boivin, Michael J. ^{[7
,8
]}

Wu, Felicia ^{[1
,9
]}

机构：

[1] Michigan State Univ, Dept Food Sci & Human Nutr, E Lansing, MI 48824 USA

[2] Univ Bergen, Ctr Int Hlth, Bergen, Norway

[3] Minist Hlth, Nat Nutr Program, Kinshasa, DEM REP CONGO

[4] Univ Kinshasa, Dept Trop Med, Kinshasa, DEM REP CONGO

[5] Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97201 USA

[6] Univ Kinshasa, Dept Neurol, Kinshasa, DEM REP CONGO

[7] Michigan State Univ, Dept Psychiat, E Lansing, MI USA

[8] Michigan State Univ, Dept Neurol & Ophthalmol, E Lansing, MI USA

[9] Michigan State Univ, Agr Food & Resource Econ, E Lansing, MI 48824 USA

来源：

NATURE FOOD | 2021年 / 2卷 / 07期

关键词：

GLOBAL BURDEN; KONZO; EXPOSURE; VILLAGES; DRC;

D O I：

10.1038/s43016-021-00321-w

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Cassava cyanide-related neurocognitive impairment may persist for years in Central African children who rely on cassava as a dietary staple. In the Democratic Republic of the Congo, a cassava processing method, the 'wetting method', reduced cyanide in cassava, prevented konzo, and proved a cost-effective intervention to improve children's cognitive development. Scaling up use of the wetting method may help prevent neurocognitive impairment in millions of at-risk children in sub-Saharan Africa. A wetting method for cassava flour can further reduce cyanide exposure and its disease burden among children. The cost-effectiveness of the method in reducing cognitive disability is assessed in the Democratic Republic of the Congo.

引用

页码：469 / 472

页数：4

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