Breast carcinoma;
Long-term benefits;
Physical rehabilitation;
Psychoeducation;
State of health;
RANDOMIZED CONTROLLED-TRIAL;
RECEIVING ADJUVANT CHEMOTHERAPY;
PHYSICAL-ACTIVITY;
DEPRESSION SCALE;
HOSPITAL ANXIETY;
EORTC QLQ-C30;
EUROPEAN-ORGANIZATION;
SWEDISH-POPULATION;
REFERENCE-VALUES;
SURVIVORS;
D O I:
10.1016/j.clbc.2018.05.004
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
This trial identified the benefits on quality of life and symptoms of a 3-month exercise and education program over 24 months' follow-up among a population of 209 women treated for breast cancer. We found an improvement in quality of life and symptoms after rehabilitation in the experimental group and a maintenance of these improvements during the 2 years of follow-up. Background: Various clinical trials have demonstrated the benefits of physical training offered during and/or after breast cancer treatments. However, given the variety of adverse events that may be encountered, physical training could be combined with psychologic, relational, and social guidance. This kind of multidisciplinary program, as well as its long-term effects, have been little studied so far. Therefore, the objective of our study was to determine the benefits at 3, 6, 12, and 24 months of a 3-month exercise and education program among women after breast cancer treatment. Patients and Methods: Two hundred nine outpatients treated for primary breast carcinoma were divided into a control group (n = 106) and an experimental group (n = 103) which underwent a 3-month rehabilitation program including physical training and psychoeducational sessions. The assessments, performed before the program and at 3, 6, 12, and 24 months after inclusion, included validated questionnaires on quality of life and symptoms. Results: The analyses revealed an improvement in quality of life and symptoms after the exercise and education program within the experimental group and a maintenance of these improvements during the 2 years of follow-up. These improvements were significantly better than those in the control group, clearly demonstrating that the program has benefits. Conclusion: This trial identified the benefits of a well-detailed 3-month exercise and education program over 24 months' follow-up among women after breast cancer treatment.
机构:
Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OHComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Alfano C.M.
Smith A.W.
论文数: 0引用数: 0
h-index: 0
机构:
DCCPS, Outcomes Research Branch, National Cancer Institute, Bethesda, MDComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Smith A.W.
Irwin M.L.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CTComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Irwin M.L.
Bowen D.J.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Bowen D.J.
Sorensen B.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Sorensen B.
Reeve B.B.
论文数: 0引用数: 0
h-index: 0
机构:
DCCPS, Outcomes Research Branch, National Cancer Institute, Bethesda, MDComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Reeve B.B.
Meeske K.A.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Preventive Medicine and USC, Keck School of Medicine, University of Southern California, Los Angeles, CAComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Meeske K.A.
Bernstein L.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Preventive Medicine and USC, Keck School of Medicine, University of Southern California, Los Angeles, CAComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Bernstein L.
Baumgartner K.B.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Epidemiology and Clinical Information Sciences, University of Louisville, Louisville, KYComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Baumgartner K.B.
Ballard-Barbash R.
论文数: 0引用数: 0
h-index: 0
机构:
Outcomes Research Branch ARP, National Cancer Institute, Bethesda, MDComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Ballard-Barbash R.
Malone K.E.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Malone K.E.
McTiernan A.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Bicego, Deanna
Brown, Kathy
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Brown, Kathy
Ruddick, Moraine
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Ruddick, Moraine
Storey, Dara
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Storey, Dara
Wong, Corinne
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Wong, Corinne
Harris, Susan R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
机构:
Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OHComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Alfano C.M.
Smith A.W.
论文数: 0引用数: 0
h-index: 0
机构:
DCCPS, Outcomes Research Branch, National Cancer Institute, Bethesda, MDComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Smith A.W.
Irwin M.L.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CTComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Irwin M.L.
Bowen D.J.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Bowen D.J.
Sorensen B.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Sorensen B.
Reeve B.B.
论文数: 0引用数: 0
h-index: 0
机构:
DCCPS, Outcomes Research Branch, National Cancer Institute, Bethesda, MDComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Reeve B.B.
Meeske K.A.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Preventive Medicine and USC, Keck School of Medicine, University of Southern California, Los Angeles, CAComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Meeske K.A.
Bernstein L.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Preventive Medicine and USC, Keck School of Medicine, University of Southern California, Los Angeles, CAComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Bernstein L.
Baumgartner K.B.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Epidemiology and Clinical Information Sciences, University of Louisville, Louisville, KYComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Baumgartner K.B.
Ballard-Barbash R.
论文数: 0引用数: 0
h-index: 0
机构:
Outcomes Research Branch ARP, National Cancer Institute, Bethesda, MDComprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Ballard-Barbash R.
Malone K.E.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
Malone K.E.
McTiernan A.
论文数: 0引用数: 0
h-index: 0
机构:
Fred Hutchinson Cancer Research Center, Seattle, WA 98109Comprehensive Cancer Center, School of Public Health, Ohio State University, Columbus, OH
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Bicego, Deanna
Brown, Kathy
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Brown, Kathy
Ruddick, Moraine
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Ruddick, Moraine
Storey, Dara
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Storey, Dara
Wong, Corinne
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada
Wong, Corinne
Harris, Susan R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, CanadaUniv British Columbia, Fac Med, Dept Phys Therapy, Vancouver, BC V6T 1Z3, Canada