A Domino Enyne/IMDA Approach to the Core Structure of (-) Vinigrol

被引：25

作者：

Betkekar, Vipul V. ^{[1
]}

Sayyad, Ashik A. ^{[1
]}

Kaliappan, Krishna P. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India

来源：

ORGANIC LETTERS | 2014年 / 16卷 / 21期

关键词：

CLOSING METATHESIS APPROACH; VIRGARIA-NIGRA; RING-SYSTEM; CONSTRUCTION; SKELETON; REARRANGEMENT; CYCLIZATION; FRAMEWORK; STRATEGY; FUNGUS;

D O I：

10.1021/ol502497n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report here an enantioselective formal synthesis of vinigrol involving a 1-2-3 strategy: one pot and two reactions with the formation of three rings leading to the core structure of vinigrol from its stereochemically well-defined acyclic precursor.

引用

页码：5540 / 5543

页数：4