1-(Hydroxymethyl)-1H-benzotriazole: An Efficient Ligand for Copper-Catalyzed Ullmann-Type Coupling Reaction Leading to Expeditious Synthesis of Diverse Benzoxazoles and Benzothiazoles

被引：7

作者：

Singh, Mala ^{[1
]}

Bose, Priyanka ^{[1
]}

Singh, Anoop S. ^{[1
]}

Tiwari, Vinod K. ^{[1
]}

机构：

[1] Banaras Hindu Univ, Inst Sci, Dept Chem, Varanasi 221005, Uttar Pradesh, India

来源：

CHEMISTRYSELECT | 2019年 / 4卷 / 33期

关键词：

Benzotriazole; Benzothiazole; Benzoxazole; Coupling; Cyclization; ALPHA-KETOHETEROCYCLIC INHIBITORS; BENZOTRIAZOLE RING-CLEAVAGE; HUMAN NEUTROPHIL ELASTASE; IN-VITRO; O-ARYLATION; ANTITUMOR; DESIGN; BENZIMIDAZOLES; CHEMISTRY; PROTOCOL;

D O I：

10.1002/slct.201902420

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cu-catalyzed Ullmann coupling was performed for the facile synthesis of diverse benzoxazoles and benzothiazoles in the presence of 1-(hydroxymethyl)-1H-benzotriazole as ligand and K2CO3 as base in anhydrous DMF at 120 degrees C.

引用

页码：9627 / 9631

页数：5

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