Current Research of Trichinellosis in China

被引:101
作者
Bai, Xue [1 ]
Hu, Xiaoxiang [1 ]
Liu, Xiaolei [1 ]
Tang, Bin [1 ]
Liu, Mingyuan [1 ,2 ]
机构
[1] Jilin Univ, Inst Zoonosis, Key Lab Zoonosis Res, Minist Educ, Changchun, Jilin, Peoples R China
[2] Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Jiangsu, Peoples R China
关键词
trichinellosis; diagnosis; vaccine; immune-related disease; China; EXCRETORY-SECRETORY PROTEINS; SPIRALIS NUDIX HYDROLASE; PROTEASE-LIKE PROTEIN; CYSTATIN-LIKE PROTEIN; TRICHINELLA-SPIRALIS; PROTECTIVE IMMUNITY; SERINE-PROTEASE; DIAGNOSTIC ANTIGENS; PARASITIC DISEASES; EPIDEMIOLOGY;
D O I
10.3389/fmicb.2017.01472
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Trichinellosis, caused by Trichinella, is an emerging or re-emerging zoonotic parasitic disease, which is distributed worldwide with major socio-economic importance in some developing countries. In particular, it has been calculated that more than 40 million people are at risk of Trichinella infection in China. This review summarizes the current information on the epidemiology, laboratory diagnosis and vaccines of trichinellosis in China. Moreover, study of the treatment potential of using Trichinella for immune-related diseases and cancer, as well as the transcription and post-transcription modification of Trichinella were also collected, providing viewpoints for future investigations. Current advances in research will help us to develop new strategies for the prevention and control of trichinellosis and may potentially yield biological agents for treating other diseases.
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页数:7
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