Tigecycline Treatment of Multi-Drug-Resistant Corynebacterium jeikeium Infection in a Child With Relapsing and Refractory Acute Lymphoblastic Leukemia

被引：22

作者：

Dinleyici, Ener Cagri ^{[1
]}

Yargic, Zeynel Abidin ^{[1
]}

Bor, Ozcan ^{[2
]}

Kiremitci, Abdurrahman ^{[3
]}

Durmaz, Gul ^{[3
]}

机构：

[1] Eskisehir Osmangazi Univ, Fac Med, Dept Pediat, TR-26480 Eskisehir, Turkey

[2] Eskisehir Osmangazi Univ, Fac Med, Dept Pediat Hematol, TR-26480 Eskisehir, Turkey

[3] Eskisehir Osmangazi Univ, Fac Med, Dept Microbiol, TR-26480 Eskisehir, Turkey

来源：

PEDIATRIC BLOOD & CANCER | 2010年 / 55卷 / 02期

关键词：

children; Corynebacterium jeikeium; leukemia; tigecycline; BACTEREMIA; CATHETERS; CANCER; SEPSIS;

D O I：

10.1002/pbc.22527

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Corynebacterium jeikeium has been recognized as an important cause of infection, particularly among neutropenic patients who have central venous catheter (CVC). Routine use of tigecycline in children is not yet approved. Here in we present a child with relapsed-refractory lymphoblastic leukemia who was successfully treated with tigecyline due to multi-drug-resistant C. jeikeium sepsis without removal of CVC. Our case highlights the use of tigecycline where there are no alternatives. Further studies regarding the efficacy and safety of tigecycline in pediatric patients are needed. Pediatr Blood Cancer. 2010;55:349-351. (C) 2010 Wiley-Liss, Inc.

引用

页码：349 / 351

页数：3

共 21 条

[1]

[Anonymous], 2006, M45A CLIN LAB STAND

[2] Tigecycline Use in Cancer Patients With Serious Infections A Report on 110 Cases From a Single Institution [J].

Chemaly, Roy F. ;

Hanmod, Santosh S. ;

Jiang, Ying ;

Rathod, Dhanesh B. ;

Mulanovich, Victor ;

Adachi, Javier A. ;

Rolston, Kenneth V. ;

Raad, Issam I. ;

Hachem, Ray Y. .

MEDICINE, 2009, 88 (04) :211-220

[3]

Falagas ME, 2009, EXPERT REV ANTI-INFE, V7, P913, DOI [10.1586/eri.09.73, 10.1586/ERI.09.73]

[4] PREDISPOSITION TO CORYNEBACTERIUM-JEIKEIUM INFECTION IN ACUTE LYMPHOBLASTIC-LEUKEMIA - A REPORT OF 2 CASES IN TRINIDAD [J].

FOSIMBANTENKHU, J ;

ORETT, FA .

MEDICAL AND PEDIATRIC ONCOLOGY, 1994, 22 (05) :350-354

[5] Safety and Efficacy of Intravenous Tigecycline in Subjects with Secondary Bacteremia: Pooled Results from 8 Phase III Clinical Trials [J].

Gardiner, David ;

Dukart, Gary ;

Cooper, Angel ;

Babinchak, Timothy .

CLINICAL INFECTIOUS DISEASES, 2010, 50 (02) :229-238

[6]

Giamarellou Helen, 2006, Expert Rev Anti Infect Ther, V4, P601, DOI 10.1586/14787210.4.4.601

[7] A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline [J].

Gordon, N. C. ;

Wareham, D. W. .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2009, 63 (04) :775-780

[8] MULTIDRUG-RESISTANT ENTEROCOCCUS FAECIUM MENINGITIS IN A TODDLER CHARACTERIZATION OF THE ORGANISM AND SUCCESSFUL TREATMENT WITH INTRAVENTRICULAR DAPTOMYCIN AND INTRAVENOUS TIGECYCLINE [J].

Jaspan, Heather B. ;

Brothers, Adam W. ;

Campbell, Angela J. P. ;

McGuire, John K. ;

Browd, Samuel R. ;

Manley, Thomas J. ;

Pak, Daniel ;

Weissman, Scott J. .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2010, 29 (04) :379-381

[9]

Karageorgopoulos Drosos E, 2009, Int J Antimicrob Agents, V34 Suppl 4, pS55, DOI 10.1016/S0924-8579(09)70569-2

[10] Fever and Neutropenia in Pediatric Patients with Cancer [J].

Meckler, Garth ;

Lindemulder, Susan .

EMERGENCY MEDICINE CLINICS OF NORTH AMERICA, 2009, 27 (03) :525-+

← 1 2 3 →