Applications of neutron and X-ray scattering to the study of biologically relevant model membranes

被引:165
|
作者
Pabst, G. [2 ]
Kucerka, N. [1 ,3 ]
Nieh, M. -P. [1 ]
Rheinstaedter, M. C. [1 ,4 ]
Katsaras, J. [1 ,5 ,6 ,7 ]
机构
[1] CNR, Canadian Neutron Beam Ctr, Steacie Inst Mol Sci, Chalk River, ON K0J 1J0, Canada
[2] Austrian Acad Sci, Inst Biophys & Nanosyst Res, A-8042 Graz, Austria
[3] Comenius Univ, Dept Phys Chem Drugs, Fac Pharm, Bratislava 83232, Slovakia
[4] McMaster Univ, Dept Phys & Astron, Hamilton, ON L8S 4M1, Canada
[5] Brock Univ, Dept Phys, St Catharines, ON L2S 3A1, Canada
[6] Univ Guelph, GuelphWaterloo Phys Inst, Guelph, ON N1G 2W1, Canada
[7] Univ Guelph, Biophys Interdept Grp, Guelph, ON N1G 2W1, Canada
关键词
Lipid bilayers; Phosphorylcholine; Cholesterol; Bicelles; Bending modulus; Neutron and X-ray diffraction; SANS and SAXS; Membrane dynamics; Inelastic neutron scattering; NUCLEAR-MAGNETIC-RESONANCE; LATERALLY HETEROGENEOUS VESICLES; HYDRATED DIPALMITOYLPHOSPHATIDYLCHOLINE BILAYERS; THERMAL-MECHANICAL FLUCTUATIONS; LIPIDIC CUBIC PHASES; HIGH-RESOLUTION NMR; MOLECULAR-DYNAMICS; TEMPERATURE-DEPENDENCE; PROTEIN DYNAMICS; EGG LECITHIN;
D O I
10.1016/j.chemphyslip.2010.03.010
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Scattering techniques, in particular electron, neutron and X-ray scattering have played a major role in elucidating the static and dynamic structure of biologically relevant membranes. Importantly, neutron and X-ray scattering have evolved to address new sample preparations that better mimic biological membranes. In this review, we will report on some of the latest model membrane results, and the neutron and X-ray techniques that were used to obtain them. Crown Copyright (C) 2010 Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:460 / 479
页数:20
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