Unusual complication after immediate postoperative intravesical mitomycin C instillation

被引:47
作者
Nieuwenhuijzen, JA [1 ]
Bex, A [1 ]
Horenblas, S [1 ]
机构
[1] Antoni Van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Urol, NL-1066 CX Amsterdam, Netherlands
关键词
intravesical chemotherapeutics; extravasation; complications; superficial bladder cancer; intravesical mitomycin C;
D O I
10.1016/S0302-2838(03)00151-9
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Immediate adjuvant Mitomycin C (MMC) instillation is routine practice in the treatment of superficial bladder cancer. Despite relative safety we describe a case of MMC extravasation after intravesical instillation. This resulted in severe continuous pain in the pelvic region without tendency of spontaneous healing, and required surgical debridement. To assess perivesical soft tissue injury prior to surgery MRI imaging turned out to be more accurate than computer tomography. Suggestions about how to avoid, diagnose and treat this symptomatic extravasation are made. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:711 / 712
页数:2
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