Transition-metal-free trifluoromethylthiolation-acylation of arynes by insertion into the C-S bonds

被引：25

作者：

Cao, Chengyao Kimmy ^{[1
]}

Tretyakov, Evgeny ^{[2
]}

Chen, Chao ^{[1
,3
]}

机构：

[1] Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Minist Educ, Beijing 100084, Peoples R China

[2] ND Zelinskii Inst Organ Chem, 47 Leninsky Prospect, Moscow 119991, Russia

[3] Nankai Univ, State Key Lab Elemento Organ Chem, Tianjin 300071, Peoples R China

来源：

GREEN SYNTHESIS AND CATALYSIS | 2021年 / 2卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Trifluoromethylthioesters; Arynes; Insertion reaction; Trifluoromethylthiolation; Acylation; BORONIC ACIDS; CATALYZED TRIFLUOROMETHYLTHIOLATION; CARBON-CARBON; ARYL; IODINATION; REAGENT; KETONES;

D O I：

10.1016/j.gresc.2020.12.001

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient procedure to access to ortho-SCF3 substituted benzophenones from arynes and tri-fluoromethylthioesters has been developed under transition-metal free conditions. This difunctionalization pro-cess involves the first insertion of arynes into the C-S & sigma;-bonds to achieve vicinal trifluoromethylthiolation-acylation of arenes in one step.

引用

页码：62 / 65

页数：4

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